HitPredict

Interactor 1: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Interactor 2: XIAP (Q9R0I6)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (rIAP-3) (rIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	14526223
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_3
Common GO terms	GO:0002020 - protease binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 810 Rn			1 496
+	Hs
		475629 UBC_HUMAN (1-533): 0: 662: 99.81		XIAP_HUMAN (1-496): 0: 582: 89.54
+	Hs
		475718 UBC_HUMAN (1-533): 0: 662: 99.81		BIRC3_HUMAN (3-496): 9.22e-72: 240: 22.74
+	Dr
		47652 Q6IS68_DANRE (222-801): 0: 703: 95.69		A0AR23_DANRE (305-495): 5.08e-25: 111: 16.27
+	Xl
		1151527 Q7SY79_XENLA (229-801): 0: 702: 96.68		MIB1_XENLA (310-495): 9.07e-22: 101: 12.99
+	Hs
		476171 UBC_HUMAN (1-533): 0: 662: 99.81		BIRC7_HUMAN (16-152): 7.05e-32: 125: 21.74
+	Hs
		476162 UBC_HUMAN (1-533): 0: 662: 99.81		MIB2_HUMAN (300-495): 8.12e-27: 116: 16.75
+	Hs
		476431 UBC_HUMAN (1-533): 0: 662: 99.81		BIRC6_HUMAN (254-441): 7.08e-26: 114: 18.50
+	Hs
		475719 UBC_HUMAN (1-533): 0: 662: 99.81		BIRC2_HUMAN (404-496): 1.49e-23: 106: 39.79
+	Hs
		476011 UBC_HUMAN (1-533): 0: 662: 99.81		MIB1_HUMAN (310-495): 7.84e-22: 101: 12.12
+	Dr
		47643 F1QHN6_DANRE (305-801): 0: 602: 96.18		A0AR23_DANRE (305-495): 5.08e-25: 111: 16.27
+	Mm
		476824 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		XIAP_MOUSE (1-496): 0: 574: 94.96
+	Hs
		474994 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		XIAP_HUMAN (1-496): 0: 582: 89.54
+	At
		1091822 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		MIP1_ARATH (342-494): 7.14e-23: 104: 17.18
+	Mm
		140018 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		BIRC3_MOUSE (3-496): 4.88e-81: 265: 24.71
+	Hs
		475022 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		BIRC3_HUMAN (3-496): 9.22e-72: 240: 22.74
+	Dr
		47653 Q7SXA3_DANRE (685-760): 2.61e-42: 152: 100.00		A0AR23_DANRE (305-495): 5.08e-25: 111: 16.27
+	Mm
		476925 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		MIB2_MOUSE (281-495): 3.77e-26: 114: 18.26
+	Hs
		171467 UBD_HUMAN (155-304): 2.44e-28: 113: 32.05		BIRC5_HUMAN (265-368): 1.67e-20: 89.6: 29.73