Interactor 1: BCAR1 (Q63767)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas)
Gene: BCAR1

Interactor 2: CRK (Q63768)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 9915838, 11146548, 9348226
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005886 - plasma membrane
GO:0015629 - actin cytoskeleton
GO:0016020 - membrane
GO:0016477 - cell migration
GO:0017124 - SH3 domain binding
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 968
Rn

1 304
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024