HitPredict

Interactor 1: M9PCG2 (M9PCG2)
Sox21b, isoform C
Gene: Sox21b

Interactor 2: Q9VCU6 (Q9VCU6)
Heterochromatin protein 1c (LD23881p)
Gene: HP1c

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	30995488
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 587 Dm			1 237
+	Dm
		1363173 Q9VUD3_DROME (1-571): 9.95e-95: 303: 100.00		Q9VCU6_DROME (1-237): 1.55e-102: 298: 100.00
+	Mm
		818771 SOX2_MOUSE (215-438): 4.36e-46: 166: 39.21		Q9DCC5_MOUSE (4-135): 9.89e-43: 144: 39.46
+	Hs
		331801 NSD2_HUMAN (129-472): 2.03e-40: 159: 10.80		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Mm
		818718 SOX2_MOUSE (215-438): 4.36e-46: 166: 39.21		CBX5_MOUSE (8-155): 9.64e-38: 132: 31.79
+	Hs
		1027207 CIC_HUMAN (61-380): 4.69e-38: 153: 19.08		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		123152 TOX4_HUMAN (85-376): 1.23e-34: 140: 14.14		CBX4_HUMAN (4-202): 4.15e-44: 157: 22.00
+	Mm
		818693 SOX2_MOUSE (215-438): 4.36e-46: 166: 39.21		CBX1_MOUSE (14-144): 1.27e-37: 131: 35.10
+	Hs
		123201 SOX2_HUMAN (215-438): 4.89e-35: 136: 37.45		CBX4_HUMAN (4-202): 4.15e-44: 157: 22.00
+	Hs
		1027054 NIPBL_HUMAN (10-492): 1.9e-36: 148: 13.31		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		1027280 TF7L2_HUMAN (32-428): 6.7e-36: 144: 13.55		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		800501 CIC_HUMAN (61-380): 4.69e-38: 153: 19.08		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Hs
		800421 NIPBL_HUMAN (10-492): 1.9e-36: 148: 13.31		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Hs
		949814 NIPBL_HUMAN (10-492): 1.9e-36: 148: 13.31		CBX1_HUMAN (14-144): 1.27e-37: 131: 35.10
+	Hs
		567688 UBF1_HUMAN (210-467): 1.87e-32: 134: 11.19		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		316171 TF7L2_HUMAN (32-428): 6.7e-36: 144: 13.55		CBX6_HUMAN (4-151): 5.58e-32: 122: 23.87
+	Hs
		727806 SOX5_HUMAN (25-331): 8.37e-40: 157: 23.49		CBX8_HUMAN (4-97): 5.53e-23: 97.6: 28.72
+	Hs
		567753 UBF1_HUMAN (210-467): 1.87e-32: 134: 11.19		MPP8_HUMAN (5-82): 2.86e-12: 67.7: 36.71
+	Hs
		818053 SOX2_HUMAN (215-438): 4.89e-35: 136: 37.45		CBX2_HUMAN (5-63): 2.6e-11: 64.7: 42.37