Protein: STX8
Syntaxin-8

Gene: STX8
Organism: Homo sapiens
Interactions: 219
UniProt ID: Q9UNK0

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1354599

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

10

20

Small-scale

0.977

High

178863

STX7
Syntaxin-7

6

20

Small-scale

0.947

High

1017849

STX4
Syntaxin-4

4

20

High-throughput

0.909

High

261740

VAMP4
Vesicle-associated membrane protein 4

4

20

Small-scale

0.909

High

1313466

VAMP8
Vesicle-associated membrane protein 8

4

20

Small-scale

0.909

High

873597

SNAA
Alpha-soluble NSF attachment protein

4

20

Small-scale

0.903

High

1205399

STX12
Syntaxin-12

4

20

High-throughput

0.903

High

306889

VAMP5
Vesicle-associated membrane protein 5

4

20

High-throughput

0.902

High

1079469

VAMP3
Vesicle-associated membrane protein 3

3

20

Small-scale

0.871

High

213061

STX6
Syntaxin-6

3

14

High-throughput

0.861

High

850607

VAMP7
Vesicle-associated membrane protein 7

3

20

Small-scale

0.861

High

1030204

STX3
Syntaxin-3

3

20

High-throughput

0.861

High

1284305

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

3

20

Small-scale

0.861

High

1306217

SNAG
Gamma-soluble NSF attachment protein

3

20

High-throughput

0.861

High

1027594

STX5
Syntaxin-5

3

20

High-throughput

0.858

High

263392

SC22B
Vesicle-trafficking protein SEC22b

2

20

High-throughput

0.811

High

269499

STX11
Syntaxin-11

2

20

High-throughput

0.811

High

1245058

STXB6
Syntaxin-binding protein 6

2

4

High-throughput

0.811

High

1261668

SCFD1
Sec1 family domain-containing protein 1

2

17

High-throughput

0.811

High

699291

STX2
Syntaxin-2

2

20

High-throughput

0.783

High

1084012

STX1A
Syntaxin-1A

2

20

High-throughput

0.783

High

1192797

CPLX4
Complexin-4

2

0

High-throughput

0.742

High

1357526

SRPRB
Signal recognition particle receptor subunit beta

4

7

High-throughput

0.699

High

151647

GOSR2
Golgi SNAP receptor complex member 2

1

20

High-throughput

0.691

High

180956

YKT6
Synaptobrevin homolog YKT6

1

20

High-throughput

0.691

High

235226

STX10
Syntaxin-10

1

15

High-throughput

0.691

High

309633

GOSR1
Golgi SNAP receptor complex member 1

1

8

High-throughput

0.691

High

926267

VAMP2
Vesicle-associated membrane protein 2

1

20

High-throughput

0.691

High

1345175

VPS45
Vacuolar protein sorting-associated protein 45

1

17

High-throughput

0.691

High

1129751

CL12A
C-type lectin domain family 12 member A

3

6

High-throughput

0.667

High

1268686

LPAR1
Lysophosphatidic acid receptor 1

3

1

High-throughput

0.667

High

1350611

STX18
Syntaxin-18

3

6

High-throughput

0.667

High

216870

CREB3
Cyclic AMP-responsive element-binding protein 3

3

3

High-throughput

0.658

High

178042

TMPS2
Transmembrane protease serine 2

3

2

High-throughput

0.653

High

1287537

AP2M1
AP-2 complex subunit mu

3

0

High-throughput

0.638

High

1290414

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

320445

SNP29
Synaptosomal-associated protein 29

2

19

High-throughput

0.628

High

803999

NSF
Vesicle-fusing ATPase

2

9

High-throughput

0.628

High

880433

AP1S2
AP-1 complex subunit sigma-2

2

3

High-throughput

0.628

High

1016714

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

2

High-throughput

0.628

High

1023451

TRDN
Triadin

2

4

High-throughput

0.628

High

1057135

EPN4
Clathrin interactor 1

2

4

High-throughput

0.628

High

1259443

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

1

High-throughput

0.628

High

1261349

TM171
Transmembrane protein 171

3

1

High-throughput

0.609

High

157677

MGST3
Glutathione S-transferase 3, mitochondrial

2

2

High-throughput

0.606

High

183311

FFAR2
Free fatty acid receptor 2

2

2

High-throughput

0.606

High

315497

CLD9
Claudin-9

2

1

High-throughput

0.606

High

326290

TSN12
Tetraspanin-12

2

3

High-throughput

0.606

High

426885

ASGR2
Asialoglycoprotein receptor 2

2

6

High-throughput

0.606

High

516175

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.606

High

816669

CXA8
Gap junction alpha-8 protein

2

6

High-throughput

0.606

High

1031809

BIK
Bcl-2-interacting killer

2

1

High-throughput

0.606

High

1068385

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.606

High

1108660

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.606

High

1147826

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

2

High-throughput

0.606

High

1160118

RNK
Ribonuclease kappa

2

1

High-throughput

0.606

High

1234001

EMC5
ER membrane protein complex subunit 5

2

2

High-throughput

0.606

High

1234951

JAGN1
Protein jagunal homolog 1

2

1

High-throughput

0.606

High

1255447

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.606

High

1255489

GP151
G-protein coupled receptor 151

2

3

High-throughput

0.606

High

1285297

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.606

High

1306108

MGST2
Microsomal glutathione S-transferase 2

2

2

High-throughput

0.606

High

1344224

SAR1A
Small COPII coat GTPase SAR1A

2

10

High-throughput

0.606

High

1348248

SCN3B
Sodium channel regulatory subunit beta-3

2

3

High-throughput

0.606

High

1357522

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.606

High

1357527

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

1

High-throughput

0.606

High

1244905

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.602

High

1291268

STALP
AMSH-like protease

2

0

High-throughput

0.602

High

592062

RAB4A
Ras-related protein Rab-4A

2

7

High-throughput

0.584

High

845806

RAB9A
Ras-related protein Rab-9A

2

12

High-throughput

0.584

High

890516

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.584

High

315089

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.580

High

1083174

KCMB1
Calcium-activated potassium channel subunit beta-1

2

0

High-throughput

0.580

High

1115472

CLM2
CMRF35-like molecule 2

2

0

High-throughput

0.580

High

1193328

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

1264848

BSND
Barttin

2

0

High-throughput

0.580

High

1293610

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.580

High

87583

C9JXZ5
Vesicle-associated membrane protein 8

1

20

High-throughput

0.575

High

1302654

MA7D2
MAP7 domain-containing protein 2

2

5

High-throughput

0.574

High

1131887

CE170
Centrosomal protein of 170 kDa

2

1

High-throughput

0.558

High

434862

CXB1
Gap junction beta-1 protein

2

6

High-throughput

0.553

High

868064

VMAT1
Chromaffin granule amine transporter

2

2

High-throughput

0.553

High

1128750

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

1135001

GORAB
RAB6-interacting golgin

2

1

High-throughput

0.553

High

1162796

TMED8
Protein TMED8

2

2

High-throughput

0.553

High

1165146

TM205
Transmembrane protein 205

2

1

High-throughput

0.553

High

1202411

RETR3
Reticulophagy regulator 3

2

1

High-throughput

0.553

High

1203280

AMGO1
Amphoterin-induced protein 1

2

2

High-throughput

0.553

High

1235517

TM86B
Lysoplasmalogenase TMEM86B

2

2

High-throughput

0.553

High

1253059

F174A
Membrane protein FAM174A

2

1

High-throughput

0.553

High

1256220

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

1262507

SSMM1
Serine-rich single-pass membrane protein 1

2

1

High-throughput

0.553

High

1289175

MTEF3
Transcription termination factor 3, mitochondrial

2

1

High-throughput

0.553

High

1300168

TM237
Transmembrane protein 237

2

1

High-throughput

0.553

High

1308581

DHRS9
Dehydrogenase/reductase SDR family member 9

2

3

High-throughput

0.553

High

1315446

B2L13
Bcl-2-like protein 13

2

2

High-throughput

0.553

High

1326915

MFF
Mitochondrial fission factor

2

1

High-throughput

0.553

High

1345963

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1356003

ERRFI
ERBB receptor feedback inhibitor 1

1

2

Small-scale

0.552

High

157148

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

5

High-throughput

0.536

High

169666

BET1
BET1 homolog

1

14

High-throughput

0.536

High

451605

CLCA
Clathrin light chain A

1

1

High-throughput

0.536

High

507314

LAMP1
Lysosome-associated membrane glycoprotein 1

1

11

High-throughput

0.536

High

921775

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.536

High

1021969

SEC20
Vesicle transport protein SEC20

1

5

High-throughput

0.536

High

1053455

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

1

High-throughput

0.536

High

1088483

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

1

High-throughput

0.536

High

1131038

SNP47
Synaptosomal-associated protein 47

1

1

High-throughput

0.536

High

1133598

STXB5
Syntaxin-binding protein 5

1

3

High-throughput

0.536

High

1139812

PLPP4
Phospholipid phosphatase 4

1

1

High-throughput

0.536

High

1298737

TMM74
Transmembrane protein 74

1

3

High-throughput

0.536

High

1348838

USE1
Vesicle transport protein USE1

1

3

High-throughput

0.536

High

1357523

TMM98
Transmembrane protein 98

1

1

High-throughput

0.536

High

182052

GPR42
G-protein coupled receptor 42

1

3

High-throughput

0.515

High

274141

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

944007

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1222718

TM192
Transmembrane protein 192

1

0

High-throughput

0.513

High

1298497

MBOA7
Lysophospholipid acyltransferase 7

1

0

High-throughput

0.513

High

1315688

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1349941

CSC1
Calcium permeable stress-gated cation channel 1

1

0

High-throughput

0.513

High

476569

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

282261

SEGN
Secretagogin

1

3

High-throughput

0.489

High

864930

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

1

1

High-throughput

0.489

High

1224842

FAM9C
Protein FAM9C

1

5

High-throughput

0.489

High

1284485

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

2

High-throughput

0.489

High

1306293

MDFI
MyoD family inhibitor

1

1

High-throughput

0.489

High

360543

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.481

High

781309

AQP2
Aquaporin-2

1

14

Small-scale

0.481

High

1037771

AQP6
Aquaporin-6

1

15

High-throughput

0.481

High

1326310

ELOV4
Very long chain fatty acid elongase 4

1

8

High-throughput

0.481

High

206167

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

350685

RASK
GTPase KRas

1

10

High-throughput

0.479

High

364478

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.479

High

375090

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

436574

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

526096

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

527887

LAMP2
Lysosome-associated membrane glycoprotein 2

1

11

High-throughput

0.479

High

545700

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564739

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

582558

NUCL
Nucleolin

1

1

High-throughput

0.479

High

592581

RAB5A
Ras-related protein Rab-5A

1

12

High-throughput

0.479

High

844799

RAB5C
Ras-related protein Rab-5C

1

13

High-throughput

0.479

High

845352

RAB7A
Ras-related protein Rab-7a

1

16

High-throughput

0.479

High

892681

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894590

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

901051

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

916076

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

951458

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

965897

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1021836

TP4A2
Protein tyrosine phosphatase type IVA 2

1

3

Small-scale

0.479

High

1133273

HECD3
E3 ubiquitin-protein ligase HECTD3

1

2

Small-scale

0.479

High

1152193

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1183611

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1188448

ATG9A
Autophagy-related protein 9A

1

5

High-throughput

0.479

High

1198222

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

1230428

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.479

High

1240363

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.479

High

1240840

RN149
E3 ubiquitin-protein ligase RNF149

1

6

High-throughput

0.479

High

1284169

LRC59
Leucine-rich repeat-containing protein 59

1

8

High-throughput

0.479

High

1303635

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

1313106

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1330990

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1333622

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1345091

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1350527

ANFY1
Rabankyrin-5

1

2

High-throughput

0.479

High

1357141

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.479

High

1357521

LAMP3
Lysosome-associated membrane glycoprotein 3

1

11

High-throughput

0.479

High

173321

S22A2
Solute carrier family 22 member 2

1

0

Small-scale

0.460

High

1354464

CLN8
Protein CLN8

1

0

Small-scale

0.460

High

168081

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

529912

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

0.458

High

648930

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

1264895

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

59706

WDR91
WD repeat-containing protein 91

1

2

High-throughput

0.457

High

968241

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

4

High-throughput

0.445

High

1250909

SCAM5
Secretory carrier-associated membrane protein 5

1

4

Small-scale

0.445

High

1110128

AR13B
ADP-ribosylation factor-like protein 13B

1

6

High-throughput

0.439

High

1343536

S35C2
Solute carrier family 35 member C2

1

3

High-throughput

0.439

High

547369

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.437

High

796452

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

1

Small-scale

0.437

High

941580

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

1146961

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

1203906

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

1328889

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

1329325

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

1346210

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

1349720

TM216
Transmembrane protein 216

1

4

High-throughput

0.437

High

1350584

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

5

High-throughput

0.437

High

1354861

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1357520

CE164
Centrosomal protein of 164 kDa

1

2

High-throughput

0.437

High

750916

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.426

High

1296697

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

276507

FACE1
CAAX prenyl protease 1 homolog

2

0

High-throughput

0.328

High

1037115

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

1333905

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

1297866

JSPR1
Junctional sarcoplasmic reticulum protein 1

2

0

High-throughput

0.320

High

134640

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.316

High

830526

STAR
Steroidogenic acute regulatory protein, mitochondrial

2

0

High-throughput

0.316

High

992211

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

0

High-throughput

0.316

High

1170495

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.316

High

1230627

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

2

0

High-throughput

0.316

High

1252745

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

1299291

MCEE
Methylmalonyl-CoA epimerase, mitochondrial

2

0

High-throughput

0.316

High

1328492

STMN4
Stathmin-4

2

0

High-throughput

0.316

High

1334665

CERS4
Ceramide synthase 4

2

0

High-throughput

0.316

High

1357524

CIA30
Complex I intermediate-associated protein 30, mitochondrial

2

0

High-throughput

0.316

High

358927

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.279

Low

940764

NOP14
Nucleolar protein 14

1

0

High-throughput

0.279

Low

1025709

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.279

Low

1167248

DPPA3
Developmental pluripotency-associated protein 3

1

0

High-throughput

0.279

Low

1184485

CENPQ
Centromere protein Q

1

0

High-throughput

0.279

Low

1290249

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

1313883

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.279

Low

1316364

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

1328961

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.279

Low

1345623

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

1357525

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

Small-scale

0.279

Low

1347152

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.269

Low

1219114

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024