HitPredict

Interactor 1: NR2E1 (Q64104)
Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (mTll)
Gene: NR2E1

Interactor 2: BC11A (Q9QYE3)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9)
Gene: Bcl11a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23975195
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 385 Mm			1 773
+	Hs
		563312 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		ZNF16_HUMAN (4-402): 8.65e-122: 382: 14.39
+	Hs
		1239545 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		ZFP62_HUMAN (1-402): 1.04e-102: 338: 13.40
+	Hs
		782648 HNF4A_HUMAN (2-383): 1.93e-95: 294: 29.90		ZN471_HUMAN (371-638): 1.74e-42: 165: 15.79
+	Hs
		1328482 NR2E1_HUMAN (1-385): 2.95e-135: 393: 98.96		BC11A_HUMAN (150-251): 5e-09: 62.1: 13.59
+	Hs
		563496 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		ZNF22_HUMAN (371-435): 1.83e-31: 124: 40.00
+	Dm
		66202 7UP1_DROME (9-384): 1.22e-106: 325: 35.11		A8JV11_DROME (84-208): 4.12e-09: 62.5: 30.23
+	Hs
		490115 COT1_HUMAN (4-383): 2.8e-106: 320: 36.58		BC11A_HUMAN (150-251): 5e-09: 62.1: 13.59
+	Hs
		490114 COT1_HUMAN (4-383): 2.8e-106: 320: 36.58		BC11B_HUMAN (435-510): 6.48e-09: 61.5: 5.20
+	Hs
		369638 ESR1_HUMAN (8-385): 5.17e-96: 300: 29.06		OZF_HUMAN (390-445): 9.57e-16: 80.6: 23.21
+	Hs
		622833 COT2_HUMAN (5-383): 6.2e-102: 309: 34.83		BC11A_HUMAN (150-251): 5e-09: 62.1: 13.59
+	Hs
		368935 ESR1_HUMAN (8-385): 5.17e-96: 300: 29.06		ZN182_HUMAN (48-206): 8.67e-10: 64.2: 15.85
+	Hs
		1067399 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		OZF_HUMAN (390-445): 9.57e-16: 80.6: 23.21
+	Hs
		1328484 NR2E3_HUMAN (8-382): 9.94e-96: 293: 42.78		BC11A_HUMAN (150-251): 5e-09: 62.1: 13.59
+	Hs
		490074 NR2F6_HUMAN (2-383): 3.57e-95: 291: 34.99		BC11A_HUMAN (150-251): 5e-09: 62.1: 13.59
+	Hs
		1269362 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		ZN845_HUMAN (666-773): 3.65e-10: 65.7: 9.09
+	Mm
		1142654 ERR2_MOUSE (9-383): 9.17e-90: 278: 28.53		Q6P5E3_MOUSE (337-433): 1.65e-09: 63.5: 40.21
+	Hs
		1269554 ESR2_HUMAN (2-382): 2.78e-88: 278: 26.75		BC11B_HUMAN (435-510): 6.48e-09: 61.5: 5.20