Protein: LRC25
Leucine-rich repeat-containing protein 25 (Monocyte and plasmacytoid-activated protein)

Gene: LRC25, LRRC25
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q8N386

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0015630 - microtubule cytoskeleton
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636237

MAL
Myelin and lymphocyte protein

2

1

High-throughput

0.606

High

669025

FPR2
N-formyl peptide receptor 2

2

1

High-throughput

0.606

High

770888

OPRM
Mu-type opioid receptor

2

1

High-throughput

0.606

High

1292106

ANR46
Ankyrin repeat domain-containing protein 46

2

1

High-throughput

0.606

High

1324868

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

1

High-throughput

0.606

High

331478

APOL3
Apolipoprotein L3

2

0

High-throughput

0.580

High

692231

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.580

High

949010

SC61G
Protein transport protein Sec61 subunit gamma

2

0

High-throughput

0.580

High

1203723

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

1245879

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.580

High

1251705

SPNS3
Protein spinster homolog 3

2

0

High-throughput

0.580

High

1324837

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.580

High

1324841

YIPF6
Protein YIPF6

2

0

High-throughput

0.580

High

1324848

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

2

0

High-throughput

0.580

High

1324857

TACAN
Transmembrane protein 120A

2

0

High-throughput

0.580

High

1324867

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.580

High

1324876

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.580

High

345093

RIGI
Antiviral innate immune response receptor RIG-I

2

0

Small-scale

0.559

High

641465

CD72
B-cell differentiation antigen CD72

2

1

High-throughput

0.553

High

170517

RAB7L
Ras-related protein Rab-7L1

1

2

High-throughput

0.536

High

227023

MCAT
Mitochondrial carnitine/acylcarnitine carrier protein

1

8

High-throughput

0.536

High

252885

EXOC3
Exocyst complex component 3

1

1

High-throughput

0.536

High

292170

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

7

High-throughput

0.536

High

552037

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.536

High

552307

ADT3
ADP/ATP translocase 3

1

5

High-throughput

0.536

High

565663

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

755595

TTK
Dual specificity protein kinase TTK

1

1

High-throughput

0.536

High

839318

MTOR
Serine/threonine-protein kinase mTOR

1

3

High-throughput

0.536

High

997030

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.536

High

1008233

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

High-throughput

0.536

High

1023366

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

1102206

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.536

High

1108606

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.536

High

1145007

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.536

High

1191882

TBB8
Tubulin beta-8 chain

1

1

High-throughput

0.536

High

1225722

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

1

High-throughput

0.536

High

1231846

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

2

High-throughput

0.536

High

1259345

TBA1A
Tubulin alpha-1A chain

1

2

High-throughput

0.536

High

1288627

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

1

High-throughput

0.536

High

1317070

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

1

High-throughput

0.536

High

1324840

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.536

High

1324850

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.536

High

1324852

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.536

High

1324858

AP1M1
AP-1 complex subunit mu-1

1

2

High-throughput

0.536

High

1324865

AT131
Endoplasmic reticulum transmembrane helix translocase

1

1

High-throughput

0.536

High

1324871

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

2

High-throughput

0.536

High

1324883

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.536

High

1324890

ORNT1
Mitochondrial ornithine transporter 1

1

8

High-throughput

0.536

High

1324892

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.536

High

1324893

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

High-throughput

0.536

High

1324894

AP1M2
AP-1 complex subunit mu-2

1

2

High-throughput

0.536

High

62982

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

127136

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.513

High

194836

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

231504

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.513

High

254296

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.513

High

271723

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

317889

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.513

High

322741

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.513

High

334055

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.513

High

562802

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.513

High

609743

LEG3
Galectin-3

1

0

High-throughput

0.513

High

637924

NF1
Neurofibromin

1

0

High-throughput

0.513

High

665112

COT2
COUP transcription factor 2

1

0

High-throughput

0.513

High

755498

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.513

High

800221

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.513

High

841215

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.513

High

884673

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

897591

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.513

High

902208

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.513

High

905621

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

941932

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.513

High

963577

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

1101175

CLN3
Battenin

1

0

High-throughput

0.513

High

1129555

ESPL1
Separin

1

0

High-throughput

0.513

High

1133213

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.513

High

1154056

MSMO1
Methylsterol monooxygenase 1

1

0

High-throughput

0.513

High

1179912

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.513

High

1211173

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.513

High

1228354

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.513

High

1228835

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.513

High

1233643

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.513

High

1243018

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.513

High

1243312

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

1252806

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.513

High

1289007

NLRX1
NLR family member X1

1

0

High-throughput

0.513

High

1293727

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.513

High

1306900

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.513

High

1313085

T183A
Transmembrane protein 183A

1

0

High-throughput

0.513

High

1316743

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

High-throughput

0.513

High

1322591

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.513

High

1324823

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.513

High

1324827

FLCN
Folliculin

1

0

High-throughput

0.513

High

1324832

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

0

High-throughput

0.513

High

1324833

ELYS
Protein ELYS

1

0

High-throughput

0.513

High

1324835

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.513

High

1324836

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.513

High

1324842

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

1324845

VPS50
Syndetin

1

0

High-throughput

0.513

High

1324849

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

1324855

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.513

High

1324859

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

1324860

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.513

High

1324862

CENPH
Centromere protein H

1

0

High-throughput

0.513

High

1324866

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

1324869

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.513

High

1324870

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.513

High

1324874

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.513

High

1324879

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.513

High

1324881

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.513

High

1324885

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.513

High

1324887

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.513

High

1324889

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.513

High

1324891

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.513

High

318147

IPO13
Importin-13

1

1

High-throughput

0.489

High

332225

UCP5
Brain mitochondrial carrier protein 1

1

5

High-throughput

0.489

High

1041676

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

1

High-throughput

0.489

High

1109473

ATR
Serine/threonine-protein kinase ATR

1

3

High-throughput

0.489

High

1210697

KMCP1
Kidney mitochondrial carrier protein 1

1

5

High-throughput

0.489

High

1324824

S2529
Mitochondrial basic amino acids transporter

1

8

High-throughput

0.489

High

1324830

S2540
Mitochondrial glutathione transporter SLC25A40

1

8

High-throughput

0.489

High

1324847

SFXN2
Sideroflexin-2

1

1

High-throughput

0.489

High

1324856

SFXN3
Sideroflexin-3

1

1

High-throughput

0.489

High

1324864

TPC
Mitochondrial thiamine pyrophosphate carrier

1

6

High-throughput

0.489

High

1324882

XPO7
Exportin-7

1

1

High-throughput

0.489

High

1324884

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

7

High-throughput

0.489

High

1324888

AP3M1
AP-3 complex subunit mu-1

1

2

High-throughput

0.489

High

425567

ISG15
Ubiquitin-like protein ISG15

1

0

Small-scale

0.458

High

1324880

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

49796

CLRN2
Clarin-2

2

0

High-throughput

0.316

High

165183

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

328696

VAMP5
Vesicle-associated membrane protein 5

2

0

High-throughput

0.316

High

335563

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

378134

TNFA
Tumor necrosis factor

2

0

High-throughput

0.316

High

928868

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

942383

EP3B
Epididymal secretory protein E3-beta

2

0

High-throughput

0.316

High

1059082

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.316

High

1205423

DB121
Beta-defensin 121

2

0

High-throughput

0.316

High

1209967

TM201
Transmembrane protein 201

2

0

High-throughput

0.316

High

1324822

CLD19
Claudin-19

2

0

High-throughput

0.316

High

1324825

CLC1A
C-type lectin domain family 1 member A

2

0

High-throughput

0.316

High

1324828

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1324829

CNIH3
Protein cornichon homolog 3

2

0

High-throughput

0.316

High

1324834

FAM3C
Protein FAM3C

2

0

High-throughput

0.316

High

1324844

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

1324846

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

0

High-throughput

0.316

High

1324877

GPC5D
G-protein coupled receptor family C group 5 member D

2

0

High-throughput

0.316

High

1324886

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.316

High

1324838

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.299

High

164604

TNPO2
Transportin-2

1

0

High-throughput

0.279

Low

165617

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.279

Low

181640

CETN3
Centrin-3

1

0

High-throughput

0.279

Low

281228

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.279

Low

296135

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.279

Low

630569

RAB3B
Ras-related protein Rab-3B

1

0

High-throughput

0.279

Low

1032615

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.279

Low

1121124

UBE4A
Ubiquitin conjugation factor E4 A

1

0

High-throughput

0.279

Low

1131880

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

1133263

ARI5B
AT-rich interactive domain-containing protein 5B

1

0

High-throughput

0.279

Low

1147540

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

1205117

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.279

Low

1215445

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.279

Low

1230748

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1239416

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.279

Low

1247605

SAMD1
Sterile alpha motif domain-containing protein 1

1

0

High-throughput

0.279

Low

1251534

THADA
tRNA

1

0

High-throughput

0.279

Low

1254225

TBCD9
TBC1 domain family member 9

1

0

High-throughput

0.279

Low

1272935

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.279

Low

1293483

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.279

Low

1324821

GUF1
Translation factor GUF1, mitochondrial

1

0

High-throughput

0.279

Low

1324826

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.279

Low

1324831

DMXL2
DmX-like protein 2

1

0

High-throughput

0.279

Low

1324839

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.279

Low

1324843

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1324851

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.279

Low

1324853

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

1324854

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.279

Low

1324861

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.279

Low

1324863

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1324872

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.279

Low

1324873

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

1324875

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

1324878

MTFP1
Mitochondrial fission process protein 1

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025