HitPredict

Interactor 1: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: CUL3 (Q9JLV5)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22167182
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0030163 - protein catabolic process GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 442 Mm			1 768
+	Hs
		1036556 SQSTM_HUMAN (1-442): 0: 715: 89.82		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		1036554 SQSTM_HUMAN (1-442): 0: 715: 89.82		CUL1_HUMAN (18-768): 0: 707: 29.94
+	Hs
		1036555 SQSTM_HUMAN (1-442): 0: 715: 89.82		CUL2_HUMAN (30-768): 0: 670: 26.30
+	Hs
		1042234 MIB2_HUMAN (106-219): 7.47e-14: 75.9: 27.59		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		1043086 MIB1_HUMAN (105-228): 1.65e-27: 117: 27.69		CUL4A_HUMAN (10-768): 0: 801: 38.45
+	Hs
		1043444 MIB1_HUMAN (105-228): 1.65e-27: 117: 27.69		CUL4B_HUMAN (5-768): 0: 795: 36.77