Interactor 1: ISG15 (Q64339)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein)
Gene: ISG15
Interactor 2: UBP18 (Q9WTV6)
Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.12) (43 kDa ISG15-specific protease) (ISG15-specific-processing protease) (Ubl thioesterase 18)
Gene: Usp18
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24533902 |
| Identification Methods | pull down, microscale thermophoresis, enzymatic study |
| Interaction Type | direct interaction, cleavage reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UCH~ubiquitin |
| Common GO terms | GO:0005829 - cytosol GO:0009617 - response to bacterium GO:0060339 - negative regulation of type I interferon-mediated signaling pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
