Interactor 1: TGFR1 (Q64729)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (ESK2) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: Tgfbr1

Interactor 2: GDF11 (Q9Z1W4)
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)
Gene: GDF11

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16845371
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0001501 - skeletal system development
GO:0009952 - anterior/posterior pattern specification
GO:0032991 - protein-containing complex
GO:0060021 - roof of mouth development
GO:0060391 - positive regulation of SMAD protein signal transduction
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 503
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024