Protein: WDR83
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)

Gene: WDR83
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q9BRX9

Gene Ontology (top 5):
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0001666 - response to hypoxia
GO:0001843 - neural tube closure
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1412028

DHX35
Probable ATP-dependent RNA helicase DHX35

4

20

High-throughput

0.892

High

1412056

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

4

20

High-throughput

0.881

High

251031

PRP17
Pre-mRNA-processing factor 17

3

18

High-throughput

0.861

High

833556

BUD31
Protein BUD31 homolog

3

5

High-throughput

0.861

High

1111232

SNW1
SNW domain-containing protein 1

3

7

High-throughput

0.861

High

1412048

ISY1
Pre-mRNA-splicing factor ISY1 homolog

3

5

High-throughput

0.861

High

1363684

TCPW
T-complex protein 1 subunit zeta-2

4

20

High-throughput

0.797

High

1407538

TCPH
T-complex protein 1 subunit eta

4

20

High-throughput

0.797

High

1412033

DCA13
DDB1- and CUL4-associated factor 13

4

19

High-throughput

0.797

High

154435

SH2B2
SH2B adapter protein 2

3

1

High-throughput

0.770

High

610860

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.770

High

821538

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.770

High

882125

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.770

High

899557

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.770

High

1007236

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.770

High

876149

TCPE
T-complex protein 1 subunit epsilon

3

20

High-throughput

0.765

High

225493

CYH3
Cytohesin-3

3

2

High-throughput

0.751

High

1241766

PRP8
Pre-mRNA-processing-splicing factor 8

1

10

High-throughput

0.740

High

1371418

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

6

High-throughput

0.726

High

245148

AQR
RNA helicase aquarius

5

9

High-throughput

0.716

High

899206

TCPQ
T-complex protein 1 subunit theta

2

20

High-throughput

0.705

High

1250767

MPRIP
Myosin phosphatase Rho-interacting protein

2

13

High-throughput

0.705

High

1138571

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

11

High-throughput

0.691

High

1387527

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

17

High-throughput

0.691

High

1180484

C19L2
CWF19-like protein 2

4

5

High-throughput

0.691

High

1348683

SHKB1
SH3KBP1-binding protein 1

4

7

High-throughput

0.691

High

1411660

GPTC1
G patch domain-containing protein 1

4

12

High-throughput

0.691

High

1412030

SYF1
Pre-mRNA-splicing factor SYF1

4

20

High-throughput

0.691

High

351350

SYF2
Pre-mRNA-splicing factor SYF2

3

5

High-throughput

0.667

High

507346

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

9

High-throughput

0.667

High

1404352

CDC5L
Cell division cycle 5-like protein

3

14

High-throughput

0.667

High

1412020

CRNL1
Crooked neck-like protein 1

3

20

High-throughput

0.667

High

1412051

PPIE
Peptidyl-prolyl cis-trans isomerase E

3

5

High-throughput

0.667

High

1412063

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

3

3

High-throughput

0.667

High

1412059

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

2

4

High-throughput

0.644

High

1289035

CATAC
Centrosomal AT-AC splicing factor

3

0

High-throughput

0.638

High

1121507

KEAP1
Kelch-like ECH-associated protein 1

4

1

High-throughput

0.637

High

208729

SI1L1
Signal-induced proliferation-associated 1-like protein 1

4

5

High-throughput

0.630

High

1134700

NUMA1
Nuclear mitotic apparatus protein 1

4

13

High-throughput

0.630

High

1295372

GPSM1
G-protein-signaling modulator 1

4

10

High-throughput

0.630

High

1336752

RB15B
Putative RNA-binding protein 15B

4

7

High-throughput

0.630

High

1399579

ARHGH
Rho guanine nucleotide exchange factor 17

4

11

High-throughput

0.630

High

1412041

FRM4A
FERM domain-containing protein 4A

4

3

High-throughput

0.630

High

1412047

ZHX1
Zinc fingers and homeoboxes protein 1

4

4

High-throughput

0.630

High

1412062

KCTD3
BTB/POZ domain-containing protein KCTD3

4

7

High-throughput

0.630

High

973808

RUXE
Small nuclear ribonucleoprotein E

2

4

High-throughput

0.628

High

974030

RUXF
Small nuclear ribonucleoprotein F

2

18

High-throughput

0.628

High

991237

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

10

High-throughput

0.628

High

1412050

PRP19
Pre-mRNA-processing factor 19

2

20

High-throughput

0.628

High

415828

HSPB1
Heat shock protein beta-1

2

5

High-throughput

0.620

High

1128099

DHX8
ATP-dependent RNA helicase DHX8

1

20

High-throughput

0.618

High

1412014

DDX23
Probable ATP-dependent RNA helicase DDX23

1

15

High-throughput

0.618

High

298067

SPF27
Pre-mRNA-splicing factor SPF27

2

11

High-throughput

0.614

High

974189

RUXG
Small nuclear ribonucleoprotein G

2

20

High-throughput

0.611

High

244605

SI1L3
Signal-induced proliferation-associated 1-like protein 3

3

7

High-throughput

0.609

High

252155

IF4E2
Eukaryotic translation initiation factor 4E type 2

3

2

High-throughput

0.609

High

1158700

DPYL2
Dihydropyrimidinase-related protein 2

3

4

High-throughput

0.609

High

1200950

SGO2
Shugoshin 2

3

1

High-throughput

0.609

High

1201279

EAPP
E2F-associated phosphoprotein

3

1

High-throughput

0.609

High

1214979

RN187
E3 ubiquitin-protein ligase RNF187

3

3

High-throughput

0.609

High

1275921

PBIR2
PABIR family member 2

3

1

High-throughput

0.609

High

1279518

ARHG8
Neuroepithelial cell-transforming gene 1 protein

3

12

High-throughput

0.609

High

1356566

CCD12
Coiled-coil domain-containing protein 12

3

2

High-throughput

0.609

High

1356641

IASPP
RelA-associated inhibitor

3

8

High-throughput

0.609

High

1371060

ARHG2
Rho guanine nucleotide exchange factor 2

3

12

High-throughput

0.609

High

1400366

NEK1
Serine/threonine-protein kinase Nek1

3

12

High-throughput

0.609

High

1410071

USB1
U6 snRNA phosphodiesterase 1

3

2

High-throughput

0.609

High

1412015

YJU2
Splicing factor YJU2

3

6

High-throughput

0.609

High

1412027

RIMS4
Regulating synaptic membrane exocytosis protein 4

3

2

High-throughput

0.609

High

1412043

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

3

1

High-throughput

0.609

High

1412052

EXO1
Exonuclease 1

3

1

High-throughput

0.609

High

1066010

VAC14
Protein VAC14 homolog

2

11

High-throughput

0.606

High

814852

CUX1
Homeobox protein cut-like 1

3

14

High-throughput

0.599

High

109501

G5E9A7
DM1 locus, WD repeat containing

1

20

High-throughput

0.594

High

246121

KIF1B
Kinesin-like protein KIF1B

1

7

High-throughput

0.594

High

992936

RACK1
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.587

High

1392102

TOE1
Target of EGR1 protein 1

1

1

High-throughput

0.587

High

855743

CRK
Adapter molecule crk

3

3

High-throughput

0.585

High

281404

GGYF1
GRB10-interacting GYF protein 1

2

7

High-throughput

0.574

High

351161

ECD
Protein ecdysoneless homolog

2

3

High-throughput

0.574

High

1256725

NKAP1
Uncharacterized protein NKAPD1

2

2

High-throughput

0.574

High

1290687

ZCH18
Zinc finger CCCH domain-containing protein 18

2

20

High-throughput

0.574

High

1383599

K1143
Uncharacterized protein KIAA1143

2

1

High-throughput

0.574

High

480291

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.573

High

1148548

SF3B4
Splicing factor 3B subunit 4

1

9

High-throughput

0.573

High

1251423

GGYF2
GRB10-interacting GYF protein 2

2

19

High-throughput

0.558

High

1310637

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

12

High-throughput

0.555

High

225095

TLX3
T-cell leukemia homeobox protein 3

2

3

High-throughput

0.553

High

832789

BCL6
B-cell lymphoma 6 protein

2

1

High-throughput

0.553

High

885383

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.553

High

1165309

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

9

High-throughput

0.553

High

1271399

KCTD9
BTB/POZ domain-containing protein KCTD9

2

7

High-throughput

0.553

High

1412053

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

1

High-throughput

0.553

High

854918

RECQ1
ATP-dependent DNA helicase Q1

1

18

High-throughput

0.553

High

970995

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.553

High

1227360

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.553

High

1412023

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.553

High

1412021

UBL5
Ubiquitin-like protein 5

1

0

High-throughput

0.549

High

1412016

SYTM
Threonine--tRNA ligase, mitochondrial

2

3

High-throughput

0.549

High

1412032

MDN1
Midasin

2

14

High-throughput

0.549

High

1412060

MTCL1
Microtubule cross-linking factor 1

2

10

High-throughput

0.549

High

286495

WBP4
WW domain-binding protein 4

1

7

Small-scale

0.541

High

974830

SMD3
Small nuclear ribonucleoprotein Sm D3

1

20

High-throughput

0.536

High

1412034

DJC17
DnaJ homolog subfamily C member 17

1

14

High-throughput

0.536

High

401395

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

6

Small-scale

0.533

High

1326325

NIN
Ninein

2

19

High-throughput

0.533

High

1412019

PAR6B
Partitioning defective 6 homolog beta

1

2

Small-scale

0.523

High

96868

E9PDH4
Phosphoinositide kinase, FYVE-type zinc finger containing

1

20

High-throughput

0.514

High

116681

H9XFA1
ISY1-RAB43

1

4

High-throughput

0.514

High

1412022

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

17

High-throughput

0.514

High

1412026

PDCL3
Phosducin-like protein 3

1

3

High-throughput

0.514

High

1153105

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.513

High

1412013

CRUM3
Protein crumbs homolog 3

1

1

Small-scale

0.512

High

974276

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

13

High-throughput

0.508

High

1150805

SF01
Splicing factor 1

1

5

High-throughput

0.508

High

1370624

GPKOW
G-patch domain and KOW motifs-containing protein

1

1

High-throughput

0.508

High

1412018

PAR6G
Partitioning defective 6 homolog gamma

1

2

Small-scale

0.504

High

1412031

PAR6A
Partitioning defective 6 homolog alpha

1

2

Small-scale

0.504

High

384531

CRYAA
Alpha-crystallin A chain

1

5

High-throughput

0.501

High

228925

CF410
Cilia- and flagella-associated protein 410

1

8

High-throughput

0.489

High

856892

BAG6
Large proline-rich protein BAG6

1

5

High-throughput

0.489

High

945849

EPIPL
Epiplakin

1

13

High-throughput

0.489

High

1254103

ZBT49
Zinc finger and BTB domain-containing protein 49

1

1

High-throughput

0.489

High

1348948

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

1370231

DAZL
Deleted in azoospermia-like

1

6

High-throughput

0.489

High

1381690

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.489

High

564296

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.479

High

1038348

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

11

Small-scale

0.479

High

1412038

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

1

High-throughput

0.479

High

47408

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

167382

KLF11
Krueppel-like factor 11

1

15

High-throughput

0.470

High

274728

DNJB6
DnaJ homolog subfamily B member 6

1

9

High-throughput

0.470

High

389880

TTHY
Transthyretin

1

1

High-throughput

0.470

High

570576

GFAP
Glial fibrillary acidic protein

1

6

High-throughput

0.470

High

637707

FLNA
Filamin-A

1

11

High-throughput

0.470

High

927521

ATX1
Ataxin-1

1

4

High-throughput

0.470

High

954598

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.470

High

1096194

TADBP
TAR DNA-binding protein 43

1

13

High-throughput

0.470

High

1412058

RNF11
RING finger protein 11

1

2

High-throughput

0.470

High

246908

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.464

High

347287

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.464

High

938789

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

15

High-throughput

0.464

High

1146984

PCBP2
Poly(rC)-binding protein 2

1

11

High-throughput

0.464

High

1412045

S30BP
SAP30-binding protein

1

1

High-throughput

0.464

High

1149362

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1412040

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.458

High

1412044

LTOR3
Ragulator complex protein LAMTOR3

1

0

Small-scale

0.458

High

71610

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

20

High-throughput

0.445

High

1398931

ZN830
Zinc finger protein 830

1

1

High-throughput

0.445

High

1411446

SRSF8
Serine/arginine-rich splicing factor 8

1

12

High-throughput

0.439

High

1412037

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.439

High

1412057

EXOS1
Exosome complex component CSL4

1

5

High-throughput

0.439

High

64746

TBC3B
TBC1 domain family member 3B

1

2

High-throughput

0.437

High

65207

TBC3F
TBC1 domain family member 3F

1

2

High-throughput

0.437

High

177052

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.437

High

324204

CE152
Centrosomal protein of 152 kDa

1

5

High-throughput

0.437

High

346258

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.437

High

607056

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.437

High

691835

MK03
Mitogen-activated protein kinase 3

1

4

Small-scale

0.437

High

703693

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.437

High

783652

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

13

Small-scale

0.437

High

1051044

FAK1
Focal adhesion kinase 1

1

8

High-throughput

0.437

High

1203243

ODFP2
Outer dense fiber protein 2

1

14

High-throughput

0.437

High

1215502

CE162
Centrosomal protein of 162 kDa

1

16

High-throughput

0.437

High

1226250

CP135
Centrosomal protein of 135 kDa

1

9

High-throughput

0.437

High

1228467

FTM
Protein fantom

1

16

High-throughput

0.437

High

1233138

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

4

High-throughput

0.437

High

1235508

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.437

High

1256575

CE128
Centrosomal protein of 128 kDa

1

17

High-throughput

0.437

High

1280910

CNTRL
Centriolin

1

12

High-throughput

0.437

High

1291351

LCA5
Lebercilin

1

17

High-throughput

0.437

High

1291571

HOOK3
Protein Hook homolog 3

1

9

High-throughput

0.437

High

1309486

CEP97
Centrosomal protein of 97 kDa

1

7

High-throughput

0.437

High

1314388

SLX4
Structure-specific endonuclease subunit SLX4

1

13

High-throughput

0.437

High

1331554

CE120
Centrosomal protein of 120 kDa

1

16

High-throughput

0.437

High

1351143

SP7
Transcription factor Sp7

1

11

High-throughput

0.437

High

1353133

FBF1
Fas-binding factor 1

1

17

High-throughput

0.437

High

1391167

BICD1
Protein bicaudal D homolog 1

1

10

High-throughput

0.437

High

1396184

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

15

High-throughput

0.437

High

1403067

CEP89
Centrosomal protein of 89 kDa

1

17

High-throughput

0.437

High

1412024

CEP44
Centrosomal protein of 44 kDa

1

2

High-throughput

0.437

High

1412025

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

12

High-throughput

0.437

High

1412042

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.437

High

1412049

HECD1
E3 ubiquitin-protein ligase HECTD1

1

13

High-throughput

0.437

High

1412054

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.437

High

1412055

NINL
Ninein-like protein

1

13

High-throughput

0.437

High

430296

JUN
Transcription factor Jun

1

14

High-throughput

0.407

High

833017

ETV6
Transcription factor ETV6

1

13

High-throughput

0.407

High

1119456

CASP
Protein CASP

1

19

High-throughput

0.407

High

1216333

IFFO2
Intermediate filament family orphan 2

1

4

High-throughput

0.407

High

1231578

TBC3G
TBC1 domain family member 3G

1

2

High-throughput

0.407

High

1289975

LUZP1
Leucine zipper protein 1

1

20

High-throughput

0.407

High

1387788

ARHGQ
Rho guanine nucleotide exchange factor 26

1

8

High-throughput

0.407

High

1412039

RAI14
Ankycorbin

1

14

High-throughput

0.407

High

1412017

K1671
Uncharacterized protein KIAA1671

4

0

High-throughput

0.360

High

913746

ZN140
Zinc finger protein 140

3

0

High-throughput

0.347

High

1381308

PSMG2
Proteasome assembly chaperone 2

3

0

High-throughput

0.347

High

1412036

AKIP
Small ribosomal subunit protein mS38

2

0

High-throughput

0.328

High

1412046

DACH1
Dachshund homolog 1

2

0

High-throughput

0.328

High

220294

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

225679

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.316

High

783747

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

1288883

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

1412029

F124B
Protein FAM124B

2

0

High-throughput

0.316

High

505108

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

1412035

SPAT6
Spermatogenesis-associated protein 6

1

0

High-throughput

0.279

Low

291697

XRP2
Protein XRP2

1

0

High-throughput

0.269

Low

160011

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

301666

WFS1
Wolframin

1

0

High-throughput

0.268

Low

622259

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

1279722

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1360737

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1382686

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.268

Low

184316

NPHP1
Nephrocystin-1

1

0

High-throughput

0.249

Low

245359

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.249

Low

290130

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.249

Low

342025

CEP43
Centrosomal protein 43

1

0

High-throughput

0.249

Low

1143500

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.249

Low

1178002

MOONR
Protein moonraker

1

0

High-throughput

0.249

Low

1397100

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

1367941

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.238

Low

1412061

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025