HitPredict

Interactor 1: STEA3 (Q658P3)
Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde)
Gene: STEAP3

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 258
+	Hs
		436358 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		1145571 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66
+	Hs
		892429 STEA3_HUMAN (1-488): 0: 786: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		951075 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		925351 STEA3_HUMAN (1-488): 0: 786: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		914133 STEA3_HUMAN (1-488): 0: 786: 100.00		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		900577 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545438 STEA3_HUMAN (1-488): 0: 786: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		894124 STEA3_HUMAN (1-488): 0: 786: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564568 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		1145579 STEA3_HUMAN (1-488): 0: 786: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26