HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: CEP85 (Q6P2H3)
Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21)
Gene: CEP85

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0007099 - centriole replication
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 762
+	Hs
		1132310 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CE85L_HUMAN (33-762): 5.08e-44: 172: 33.38
+	Hs
		1017538 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		KIF5A_HUMAN (259-749): 5.37e-25: 113: 15.35
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46
+	Hs
		1146002 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKB_HUMAN (358-757): 3.54e-20: 98.5: 12.80
+	Hs
		1137872 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKA_HUMAN (390-752): 1.01e-18: 93.6: 12.47
+	Hs
		1113789 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		GRDN_HUMAN (340-687): 7.66e-13: 74.6: 20.46
+	Hs
		1145962 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		DAPLE_HUMAN (385-740): 2.37e-12: 73: 18.35
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46
+	Hs
		1067423 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		EEA1_HUMAN (92-676): 3.33e-18: 91.8: 10.59
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46
+	Hs
		724687 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06
+	Hs
		1113782 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		GRDN_HUMAN (340-687): 7.66e-13: 74.6: 20.46
+	Hs
		1051301 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		DCTN1_HUMAN (504-754): 1.94e-12: 73.2: 13.78
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (260-622): 2.7e-09: 63.1: 14.80
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (170-663): 5.35e-13: 75: 12.07
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (260-622): 2.7e-09: 63.1: 14.80
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (125-577): 7.63e-12: 71.4: 9.41
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (115-496): 3.81e-10: 66: 7.21