HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, 16189514, 9472028, 32707033, 23602568, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, pull down, tandem affinity purification and 2 others

more...
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024