HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: MRCKB (Q9Y5S2)
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)
Gene: CDC42BPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Hs			1 1711
+	Hs
		1137872 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKA_HUMAN (1-1710): 0: 1386: 60.78
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		728513 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		725242 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		568689 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Mm
		93559 DESP_MOUSE (212-1059): 2.19e-26: 120: 14.43		TAOK2_MOUSE (50-929): 2.77e-126: 429: 16.08
+	Hs
		568568 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		528359 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		610795 MYH2_HUMAN (474-1138): 1.99e-36: 152: 13.64		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		522538 MYH1_HUMAN (474-1139): 2.79e-35: 148: 12.92		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		148460 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148359 DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148534 CENPF_HUMAN (101-707): 3.1e-10: 67: 13.08		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		725010 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		610802 MYH4_HUMAN (784-1139): 4.49e-17: 89.4: 9.55		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		725079 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		ST38L_HUMAN (1-421): 5.35e-120: 388: 37.93
+	Hs
		568567 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		1344953 DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99		LATS2_HUMAN (66-375): 4.05e-70: 259: 40.34
+	Hs
		724810 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		ROCK1_HUMAN (360-1074): 6.44e-17: 89.6: 13.02