HitPredict

Interactor 1: MAP1S (Q66K74)
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain]
Gene: MAP1S

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	25900982, 28514442, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1059 Hs			1 605
+	Hs
		1146258 MAP1S_HUMAN (16-1059): 0: 627: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		980032 IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		807876 MAP1B_HUMAN (313-1059): 3.25e-37: 155: 16.80		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Mm
		541461 MAP1B_MOUSE (604-1059): 6.19e-38: 157: 23.38		LIS1_MOUSE (174-494): 5.84e-74: 244: 21.37
+	Hs
		979963 IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		903374 KMT2C_HUMAN (472-1018): 1.3e-13: 78.1: 11.47		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		209436 MDC1_HUMAN (299-855): 4.53e-11: 69.7: 10.52		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		903152 IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33