Protein: CDT1
DNA replication factor Cdt1 (Double parked homolog) (DUP)

Gene: CDT1
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9H211

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

284348

GEMI
Geminin

24

3

Small-scale

0.992

High

1128286

MCM6
DNA replication licensing factor MCM6

6

7

Small-scale

0.952

High

888325

MCM2
DNA replication licensing factor MCM2

2

4

Small-scale

0.768

High

551253

PCNA
Proliferating cell nuclear antigen

12

1

Small-scale

0.760

High

629163

CCNA2
Cyclin-A2

7

2

Small-scale

0.751

High

668024

CDK2
Cyclin-dependent kinase 2

6

3

Small-scale

0.739

High

755790

MCM4
DNA replication licensing factor MCM4

1

6

Small-scale

0.724

High

1101898

SKP2
S-phase kinase-associated protein 2

7

0

Small-scale

0.717

High

443514

CDK1
Cyclin-dependent kinase 1

4

3

Small-scale

0.703

High

1406949

CDC6
Cell division control protein 6 homolog

4

2

Small-scale

0.689

High

1431414

DTL
Denticleless protein homolog

4

1

Small-scale

0.686

High

1007655

CCNA1
Cyclin-A1

4

2

Small-scale

0.672

High

1025292

CDK3
Cyclin-dependent kinase 3

3

3

High-throughput

0.667

High

1115052

CUL4A
Cullin-4A

3

4

Small-scale

0.640

High

1157924

DDB1
DNA damage-binding protein 1

2

2

Small-scale

0.631

High

753931

CKS2
Cyclin-dependent kinases regulatory subunit 2

2

1

High-throughput

0.628

High

956685

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

1

High-throughput

0.628

High

332045

KAT7
Histone acetyltransferase KAT7

2

1

Small-scale

0.624

High

1431422

FZR1
Fizzy-related protein homolog

2

1

Small-scale

0.624

High

243734

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

2

0

Small-scale

0.619

High

1410131

GRWD1
Glutamate-rich WD repeat-containing protein 1

2

0

Small-scale

0.619

High

1104367

ORC2
Origin recognition complex subunit 2

2

1

Small-scale

0.611

High

1387268

HDA11
Histone deacetylase 11

2

0

Small-scale

0.598

High

831409

CCNF
Cyclin-F

2

4

High-throughput

0.584

High

1112709

CUL1
Cullin-1

2

4

Small-scale

0.584

High

95591

E2QRF9
Geminin DNA replication inhibitor

1

3

High-throughput

0.575

High

573888

CCNB1
G2/mitotic-specific cyclin-B1

1

2

Small-scale

0.561

High

1158182

MK14
Mitogen-activated protein kinase 14

1

3

Small-scale

0.561

High

1431417

BAZ1B
Tyrosine-protein kinase BAZ1B

1

2

Small-scale

0.561

High

1431418

CDC23
Cell division cycle protein 23 homolog

1

1

Small-scale

0.561

High

1431419

APC7
Anaphase-promoting complex subunit 7

1

1

Small-scale

0.561

High

1287015

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

2

0

Small-scale

0.559

High

447430

NPM
Nucleophosmin

1

0

Small-scale

0.537

High

542218

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.537

High

542649

TOP2A
DNA topoisomerase 2-alpha

1

0

Small-scale

0.537

High

1104328

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.536

High

1404388

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.536

High

164086

NDC80
Kinetochore protein NDC80 homolog

1

0

Small-scale

0.525

High

1122867

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.513

High

1151388

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.513

High

1086907

CDC20
Cell division cycle protein 20 homolog

1

1

Small-scale

0.501

High

1146262

ZMY11
Zinc finger MYND domain-containing protein 11

1

1

High-throughput

0.501

High

238749

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

1

High-throughput

0.489

High

1431424

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.489

High

219750

FOXO3
Forkhead box protein O3

1

0

Small-scale

0.480

High

1067707

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.480

High

1369206

KAT2B
Histone acetyltransferase KAT2B

1

0

Small-scale

0.480

High

1419590

NUF2
Kinetochore protein Nuf2

1

0

Small-scale

0.479

High

1431425

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.479

High

173349

XPO1
Exportin-1

1

1

High-throughput

0.479

High

186803

P73
Tumor protein p73

1

2

High-throughput

0.479

High

549236

CDK4
Cyclin-dependent kinase 4

1

4

Small-scale

0.479

High

667011

CCNE1
G1/S-specific cyclin-E1

1

3

Small-scale

0.479

High

853849

MK09
Mitogen-activated protein kinase 9

1

2

Small-scale

0.479

High

1115420

CUL4B
Cullin-4B

1

4

Small-scale

0.479

High

1431413

P63
Tumor protein 63

1

2

High-throughput

0.479

High

1431423

FAF1
FAS-associated factor 1

1

1

Small-scale

0.479

High

227665

SPOP
Speckle-type POZ protein

1

0

Small-scale

0.458

High

911101

IMA1
Importin subunit alpha-1

1

0

Small-scale

0.458

High

992328

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

1134379

IMB1
Importin subunit beta-1

1

0

Small-scale

0.458

High

1155755

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1244829

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1363086

DDB2
DNA damage-binding protein 2

1

0

Small-scale

0.458

High

1431412

CDT1
DNA replication factor Cdt1

1

0

Small-scale

0.458

High

1431420

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.458

High

1431421

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

Small-scale

0.437

High

1220946

FBX31
F-box only protein 31

1

0

Small-scale

0.301

High

63868

TPC13
Trafficking protein particle complex subunit 13

1

0

High-throughput

0.279

Low

1271307

5MP2
eIF5-mimic protein 2

1

0

High-throughput

0.279

Low

1311401

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.279

Low

1431415

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

1431416

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025