HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: ASCC3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
Gene: ASCC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30196744, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 2202
+	Mm
		93329 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		ASCC3_MOUSE (1-2201): 0: 1786: 92.05
+	Hs
		272239 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		U520_HUMAN (7-2198): 0: 1584: 37.61
+	Hs
		272085 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		U520_HUMAN (7-2198): 0: 1584: 37.61
+	Sp
		293870 CWF17_SCHPO (320-594): 1.33e-24: 107: 29.58		BRR2_SCHPO (16-2182): 0: 1346: 33.09
+	Hs
		1146582 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53
+	Hs
		786967 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84
+	Hs
		1271621 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97
+	Hs
		571547 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38
+	Hs
		786997 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84
+	Hs
		1271679 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97
+	Mm
		1194982 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		DDX42_MOUSE (274-903): 3.33e-99: 345: 13.53
+	Hs
		903410 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97
+	Mm
		1207743 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		MTREX_MOUSE (345-1187): 9.82e-90: 319: 16.14
+	Hs
		571382 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38
+	Hs
		133956 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50
+	Hs
		181721 POC1A_HUMAN (188-352): 4.31e-16: 82.8: 13.98		DDX3Y_HUMAN (1252-1734): 5.37e-90: 310: 12.50
+	Sp
		143079 CWF17_SCHPO (320-594): 1.33e-24: 107: 29.58		YE02_SCHPO (476-899): 2.61e-78: 285: 22.44