HitPredict

Interactor 1: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Interactor 2: PACN1 (Q9BY11)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: PACSIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	11431473, 20936779
Identification Methods	pull down, two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007015 - actin filament organization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 881 Hs			1 444
+	Hs
		1075791 RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		1357492 3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91		PACN2_HUMAN (1-444): 2.16e-80: 258: 61.32
+	Hs
		1148383 RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00		FNBP1_HUMAN (224-443): 9.17e-09: 59.7: 13.16
+	Hs
		1075786 RHG44_HUMAN (1-754): 4.1e-106: 348: 46.20		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		200200 SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90		SRGP3_HUMAN (25-408): 6.07e-38: 149: 11.89
+	Hs
		1075823 3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		253374 SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90		SRGP1_HUMAN (26-408): 2.71e-36: 144: 12.41
+	Hs
		200194 SRGP3_HUMAN (13-738): 1.18e-76: 272: 15.58		SRGP3_HUMAN (25-408): 6.07e-38: 149: 11.89
+	Hs
		1089301 RHG44_HUMAN (1-754): 4.1e-106: 348: 46.20		FBP1L_HUMAN (244-443): 8.15e-10: 62.8: 13.81
+	Hs
		1075787 Q1RLN5_HUMAN (53-427): 1.31e-64: 234: 17.90		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		200223 RHG24_HUMAN (181-607): 2.5e-68: 243: 19.82		SRGP3_HUMAN (25-408): 6.07e-38: 149: 11.89
+	Hs
		1075798 RHG12_HUMAN (53-427): 1.04e-63: 232: 17.90		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		63070 RHG42_HUMAN (1-719): 2.27e-84: 290: 14.59		CRKL_HUMAN (366-444): 7.4e-12: 68: 32.91
+	Dm
		112686 RG92B_DROME (1-645): 9.92e-76: 264: 25.38		M9NE16_DROME (217-442): 8.3e-09: 59.7: 13.91
+	Hs
		993032 RHG01_HUMAN (250-412): 3.19e-19: 93.6: 32.73		SRGP1_HUMAN (26-408): 2.71e-36: 144: 12.41
+	Mm
		1145001 RHG30_MOUSE (250-442): 1.87e-18: 92.8: 31.66		ITSN1_MOUSE (367-442): 1.31e-12: 72: 32.90
+	Hs
		64671 RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41		CRKL_HUMAN (366-444): 7.4e-12: 68: 32.91
+	Hs
		506542 BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54		CRKL_HUMAN (366-444): 7.4e-12: 68: 32.91