Interactor 1: GIT1 (Q68FF6)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)
Gene: GIT1

Interactor 2: ARHG7 (Q9ES28)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (PAK-interacting exchange factor beta) (p85SPR)
Gene: Arhgef7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 16959763, 19022416
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArfGap~PH, GIT_SHD~RhoGEF67_u2
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0030426 - growth cone
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 770
Mm

1 862
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024