Protein: SAFB2
Scaffold attachment factor B2 (SAF-B2)

Gene: SAFB2
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q14151

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1090223

ELAV2
ELAV-like protein 2

3

19

High-throughput

0.855

High

775077

FUS
RNA-binding protein FUS

3

20

High-throughput

0.849

High

1121675

SAFB1
Scaffold attachment factor B1

2

18

Small-scale

0.815

High

478040

SNRPA
U1 small nuclear ribonucleoprotein A

2

18

High-throughput

0.789

High

485137

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

20

High-throughput

0.789

High

794481

RBMX
RNA-binding motif protein, X chromosome

2

20

High-throughput

0.789

High

1115641

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

14

High-throughput

0.789

High

1121665

RBM39
RNA-binding protein 39

2

19

High-throughput

0.789

High

462405

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

20

High-throughput

0.776

High

1121755

ZRAN1
Ubiquitin thioesterase ZRANB1

2

10

High-throughput

0.754

High

443359

CDK1
Cyclin-dependent kinase 1

1

7

High-throughput

0.691

High

889729

CLK3
Dual specificity protein kinase CLK3

1

20

High-throughput

0.691

High

1121680

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

15

High-throughput

0.691

High

1121703

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

2

High-throughput

0.691

High

1121711

TRIB2
Tribbles homolog 2

1

7

High-throughput

0.691

High

1121723

PABP5
Polyadenylate-binding protein 5

1

14

High-throughput

0.691

High

1121726

RBM14
RNA-binding protein 14

1

19

High-throughput

0.691

High

1121705

ZFP41
Zinc finger protein 41 homolog

3

4

High-throughput

0.667

High

1121662

SAFB2
Scaffold attachment factor B2

1

17

Small-scale

0.665

High

978926

RS6
Small ribosomal subunit protein eS6

3

3

High-throughput

0.650

High

372000

MYC
Myc proto-oncogene protein

3

18

High-throughput

0.640

High

1121677

TRIP6
Thyroid receptor-interacting protein 6

2

4

High-throughput

0.628

High

1121691

CAN13
Calpain-13

2

4

High-throughput

0.628

High

1121759

CIZ1
Cip1-interacting zinc finger protein

2

8

High-throughput

0.628

High

472732

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

1032956

EWS
RNA-binding protein EWS

1

12

High-throughput

0.618

High

1100766

G3BP1
Ras GTPase-activating protein-binding protein 1

1

15

High-throughput

0.618

High

1121715

RBP56
TATA-binding protein-associated factor 2N

1

12

High-throughput

0.618

High

1121729

SRPK1
SRSF protein kinase 1

1

20

Small-scale

0.618

High

1121690

IFIX
Pyrin and HIN domain-containing protein 1

2

11

High-throughput

0.611

High

881771

DHYS
Deoxyhypusine synthase

2

0

High-throughput

0.602

High

480135

RU1C
U1 small nuclear ribonucleoprotein C

2

3

High-throughput

0.601

High

558123

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.586

High

129068

MEN1
Menin

2

5

High-throughput

0.584

High

259934

BRD4
Bromodomain-containing protein 4

2

9

High-throughput

0.584

High

396090

ESR1
Estrogen receptor

1

20

Small-scale

0.578

High

410837

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

8

High-throughput

0.576

High

911583

NCBP2
Nuclear cap-binding protein subunit 2

1

19

High-throughput

0.575

High

1016438

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.575

High

1066639

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.575

High

1121676

SF01
Splicing factor 1

1

11

High-throughput

0.575

High

1121686

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

Small-scale

0.575

High

1121708

RBCC1
RB1-inducible coiled-coil protein 1

2

20

High-throughput

0.558

High

1121739

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

20

High-throughput

0.558

High

1121745

FNDC4
Fibronectin type III domain-containing protein 4

2

6

High-throughput

0.558

High

157356

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.553

High

1121727

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

4

High-throughput

0.549

High

1121756

PNMA2
Paraneoplastic antigen Ma2

2

6

High-throughput

0.549

High

899895

FXR1
RNA-binding protein FXR1

1

11

High-throughput

0.541

High

1121707

ZSC18
Zinc finger and SCAN domain-containing protein 18

1

4

High-throughput

0.541

High

123695

MYO1C
Unconventional myosin-Ic

1

5

High-throughput

0.536

High

128224

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.536

High

130463

SPT5H
Transcription elongation factor SPT5

1

3

High-throughput

0.536

High

158652

TYB4Y
Thymosin beta-4, Y-chromosomal

1

1

High-throughput

0.536

High

166151

AIM2
Interferon-inducible protein AIM2

1

11

High-throughput

0.536

High

271520

ATG13
Autophagy-related protein 13

1

3

High-throughput

0.536

High

272655

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

14

High-throughput

0.536

High

272931

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

2

High-throughput

0.536

High

334768

IPO7
Importin-7

1

1

High-throughput

0.536

High

481279

HMGB1
High mobility group protein B1

1

18

High-throughput

0.536

High

515882

SAA1
Serum amyloid A-1 protein

1

2

High-throughput

0.536

High

542012

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

574266

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.536

High

601666

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.536

High

640878

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

5

High-throughput

0.536

High

786598

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

11

High-throughput

0.536

High

846292

MATR3
Matrin-3

1

12

High-throughput

0.536

High

948526

APC15
Anaphase-promoting complex subunit 15

1

2

High-throughput

0.536

High

968295

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

11

High-throughput

0.536

High

1065189

SSRP1
FACT complex subunit SSRP1

1

12

High-throughput

0.536

High

1113079

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1121668

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.536

High

1121674

PEA15
Astrocytic phosphoprotein PEA-15

1

3

High-throughput

0.536

High

1121681

IF16
Gamma-interferon-inducible protein 16

1

11

High-throughput

0.536

High

1121682

H2B2E
Histone H2B type 2-E

1

8

High-throughput

0.536

High

1121683

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

4

High-throughput

0.536

High

1121693

COX15
Heme A synthase COX15

1

3

High-throughput

0.536

High

1121698

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1121700

ZN677
Zinc finger protein 677

1

1

High-throughput

0.536

High

1121714

EZH1
Histone-lysine N-methyltransferase EZH1

1

9

High-throughput

0.536

High

1121716

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.536

High

1121724

RBM33
RNA-binding protein 33

1

9

High-throughput

0.536

High

1121725

ZN514
Zinc finger protein 514

1

1

High-throughput

0.536

High

1121730

MPP8
M-phase phosphoprotein 8

1

10

High-throughput

0.536

High

1121740

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.536

High

1121749

DDX21
Nucleolar RNA helicase 2

1

10

High-throughput

0.536

High

1121760

TPX2
Targeting protein for Xklp2

1

9

High-throughput

0.536

High

1121761

KLH20
Kelch-like protein 20

1

5

High-throughput

0.536

High

1121762

EMC9
ER membrane protein complex subunit 9

1

3

High-throughput

0.536

High

1121689

Q6ICH2
single-stranded DNA cytosine deaminase

2

18

High-throughput

0.533

High

881661

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.518

High

250245

VINEX
Vinexin

1

9

Small-scale

0.515

High

413815

P53
Cellular tumor antigen p53

1

6

Small-scale

0.515

High

1121669

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.515

High

1121678

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.515

High

1121718

H2B1H
Histone H2B type 1-H

1

8

High-throughput

0.515

High

387268

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

964273

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.501

High

1005360

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

6

Small-scale

0.501

High

421159

SCG1
Secretogranin-1

1

2

High-throughput

0.494

High

1100602

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.493

High

169183

QCR10
Cytochrome b-c1 complex subunit 10

1

1

High-throughput

0.489

High

317063

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

1

High-throughput

0.489

High

711889

LTK
Leukocyte tyrosine kinase receptor

1

17

High-throughput

0.489

High

1092754

MALL
MAL-like protein

1

1

High-throughput

0.489

High

1121710

JPH3
Junctophilin-3

1

4

High-throughput

0.489

High

1121720

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

2

High-throughput

0.489

High

1121731

ATGA1
Autophagy-related protein 101

1

1

High-throughput

0.489

High

1121743

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.489

High

1121754

PEN2
Gamma-secretase subunit PEN-2

1

1

High-throughput

0.489

High

1121757

ANR50
Ankyrin repeat domain-containing protein 50

1

5

High-throughput

0.489

High

1121764

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.489

High

1121663

GIT2
ARF GTPase-activating protein GIT2

1

7

High-throughput

0.481

High

608264

EGLN
Endoglin

1

0

High-throughput

0.480

High

138105

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

6

High-throughput

0.479

High

171875

ZN263
Zinc finger protein 263

1

2

Small-scale

0.479

High

188275

HDAC3
Histone deacetylase 3

1

7

Small-scale

0.479

High

223027

PRC1
Protein regulator of cytokinesis 1

1

8

High-throughput

0.479

High

247895

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

272160

OBSL1
Obscurin-like protein 1

1

14

High-throughput

0.479

High

278344

NCOR1
Nuclear receptor corepressor 1

1

13

Small-scale

0.479

High

285272

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

328003

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.479

High

330953

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

345801

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

19

High-throughput

0.479

High

352432

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

375510

RASK
GTPase KRas

1

8

High-throughput

0.479

High

406168

MYCN
N-myc proto-oncogene protein

1

17

High-throughput

0.479

High

459286

CATL1
Procathepsin L

1

2

High-throughput

0.479

High

473979

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.479

High

488788

FURIN
Furin

1

1

High-throughput

0.479

High

588670

RFA2
Replication protein A 32 kDa subunit

1

14

High-throughput

0.479

High

606752

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

669898

MCM3
DNA replication licensing factor MCM3

1

5

High-throughput

0.479

High

695431

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

765499

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.479

High

768164

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.479

High

774351

BASI
Basigin

1

7

High-throughput

0.479

High

789112

NUP62
Nuclear pore glycoprotein p62

1

5

High-throughput

0.479

High

789494

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.479

High

879077

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

8

High-throughput

0.479

High

904700

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.479

High

942604

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

16

High-throughput

0.479

High

952161

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.479

High

961723

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.479

High

979639

H4
Histone H4

1

10

High-throughput

0.479

High

982660

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

986035

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

1004554

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.479

High

1015205

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.479

High

1026373

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

1035608

KIF23
Kinesin-like protein KIF23

1

19

High-throughput

0.479

High

1067313

EP300
Histone acetyltransferase p300

1

10

High-throughput

0.479

High

1096683

RFA4
Replication protein A 30 kDa subunit

1

14

High-throughput

0.479

High

1115187

CUL4B
Cullin-4B

1

20

High-throughput

0.479

High

1121667

CUL7
Cullin-7

1

9

High-throughput

0.479

High

1121670

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1121672

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1121673

EEA1
Early endosome antigen 1

1

15

High-throughput

0.479

High

1121679

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1121684

MIDN
Midnolin

1

1

High-throughput

0.479

High

1121687

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

11

Small-scale

0.479

High

1121692

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1121694

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

1121695

BIVM
Basic immunoglobulin-like variable motif-containing protein

1

1

High-throughput

0.479

High

1121696

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.479

High

1121697

ZCH18
Zinc finger CCCH domain-containing protein 18

1

14

High-throughput

0.479

High

1121702

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

1121704

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

9

High-throughput

0.479

High

1121709

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1121712

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1121717

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

1

High-throughput

0.479

High

1121721

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1121728

LENG8
Leukocyte receptor cluster member 8

1

7

High-throughput

0.479

High

1121732

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.479

High

1121733

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1121735

FACD2
Fanconi anemia group D2 protein

1

11

High-throughput

0.479

High

1121736

ACE2
Angiotensin-converting enzyme 2

1

4

High-throughput

0.479

High

1121738

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1121742

CHM4B
Charged multivesicular body protein 4b

1

13

High-throughput

0.479

High

1121744

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1121747

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.479

High

1121748

ANLN
Anillin

1

8

High-throughput

0.479

High

1121750

TOPRS
E3 ubiquitin-protein ligase Topors

1

4

Small-scale

0.479

High

1121751

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1121752

AATF
Protein AATF

1

3

High-throughput

0.479

High

1121753

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.479

High

861159

MAP1B
Microtubule-associated protein 1B

1

13

High-throughput

0.470

High

292906

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.458

High

596649

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.458

High

843333

NSG1
Neuronal vesicle trafficking-associated protein 1

1

0

High-throughput

0.458

High

1121699

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.458

High

987628

GRB2
Growth factor receptor-bound protein 2

1

14

High-throughput

0.445

High

1119120

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

9

High-throughput

0.445

High

1121685

NCBP3
Nuclear cap-binding protein subunit 3

1

4

High-throughput

0.445

High

1121719

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

18

High-throughput

0.445

High

1121763

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.445

High

1121713

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

164334

NRP1
Neuropilin-1

1

2

High-throughput

0.437

High

273625

PHAR2
Phosphatase and actin regulator 2

1

9

High-throughput

0.437

High

870459

NPBW1
Neuropeptides B/W receptor type 1

1

1

High-throughput

0.437

High

1121664

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1121688

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.437

High

1121701

S35F2
Solute carrier family 35 member F2

1

1

Small-scale

0.437

High

1121722

CHM4C
Charged multivesicular body protein 4c

1

13

High-throughput

0.437

High

1121734

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

20

High-throughput

0.437

High

1121737

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

9

High-throughput

0.437

High

1121758

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1121666

MVP
Major vault protein

1

0

High-throughput

0.426

High

886849

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

73401

B2CML4
single-stranded DNA cytosine deaminase

1

18

High-throughput

0.407

High

1063942

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.407

High

1121671

SYLM
Leucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.407

High

1121746

GHC1
Mitochondrial glutamate carrier 1

1

2

High-throughput

0.407

High

873392

LSS
Lanosterol synthase

1

0

High-throughput

0.279

Low

1121706

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1121741

RSPH9
Radial spoke head protein 9 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025