HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 1893
+	Hs
		444460 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		281045 KRT38_HUMAN (1-430): 8.86e-77: 247: 49.77		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		280910 KRT37_HUMAN (1-429): 1.93e-75: 243: 48.25		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		444307 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		551676 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		724787 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		528413 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		444487 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		725143 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		1149398 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH2_HUMAN (1169-1882): 5.05e-23: 109: 10.61
+	Hs
		49550 A1A4E9_HUMAN (80-411): 7.5e-95: 294: 50.75		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Hs
		531529 K2C5_HUMAN (57-410): 3.29e-75: 247: 25.91		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		522534 K1C13_HUMAN (80-411): 1.72e-94: 293: 50.75		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Hs
		359462 K2C6A_HUMAN (57-424): 5.36e-75: 246: 25.20		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		1149413 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH4_HUMAN (1156-1882): 1.02e-19: 99.2: 11.08
+	Hs
		1149361 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		522624 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		522555 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Hs
		281068 KRT38_HUMAN (1-430): 8.86e-77: 247: 49.77		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		502919 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH3_HUMAN (938-1610): 2.46e-10: 68.4: 9.82