Protein: CGNL1
Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin)

Gene: CGNL1
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q0VF96

Gene Ontology (top 5):
GO:0005923 - bicellular tight junction
GO:0007015 - actin filament organization
GO:0016459 - myosin complex
GO:0032991 - protein-containing complex
GO:0051058 - negative regulation of small GTPase mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

966246

1433G
14-3-3 protein gamma

4

20

High-throughput

0.633

High

1081693

RCN2
Reticulocalbin-2

1

2

High-throughput

0.595

High

729781

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.593

High

1049236

1433F
14-3-3 protein eta

3

20

High-throughput

0.593

High

413715

P53
Cellular tumor antigen p53

2

3

High-throughput

0.584

High

276302

HMMR
Hyaluronan mediated motility receptor

2

18

High-throughput

0.574

High

1081700

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

2

High-throughput

0.574

High

1081718

NDE1
Nuclear distribution protein nudE homolog 1

2

18

High-throughput

0.574

High

971450

1433E
14-3-3 protein epsilon

2

3

High-throughput

0.561

High

1081719

NINL
Ninein-like protein

1

19

High-throughput

0.553

High

668569

APC
Adenomatous polyposis coli protein

1

9

High-throughput

0.541

High

990150

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.535

High

534983

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.515

High

1081711

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.501

High

765446

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.489

High

1081698

GRAP1
GRIP1-associated protein 1

1

19

High-throughput

0.489

High

461407

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

468308

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

487235

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

690946

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

764701

CTNB1
Catenin beta-1

1

5

High-throughput

0.479

High

1058823

ZO1
Tight junction protein 1

1

3

High-throughput

0.479

High

1081694

PDIA5
Protein disulfide-isomerase A5

1

1

High-throughput

0.470

High

1081717

WNK1
Serine/threonine-protein kinase WNK1

1

4

High-throughput

0.457

High

942583

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

10

High-throughput

0.445

High

159624

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

8

High-throughput

0.437

High

179196

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

3

Small-scale

0.437

High

189534

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

279351

TULP3
Tubby-related protein 3

1

2

High-throughput

0.437

High

445844

ENOA
Alpha-enolase

1

5

High-throughput

0.437

High

730545

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

936312

AFAD
Afadin

1

20

High-throughput

0.437

High

1070491

FCHO2
F-BAR domain only protein 2

1

3

High-throughput

0.437

High

1081695

EEA1
Early endosome antigen 1

1

19

High-throughput

0.437

High

1081696

STIL
SCL-interrupting locus protein

1

1

High-throughput

0.437

High

1081697

RGPA2
Ral GTPase-activating protein subunit alpha-2

1

3

High-throughput

0.437

High

1081699

CP135
Centrosomal protein of 135 kDa

1

19

High-throughput

0.437

High

1081701

SAS6
Spindle assembly abnormal protein 6 homolog

1

17

High-throughput

0.437

High

1081703

SYNE3
Nesprin-3

1

20

High-throughput

0.437

High

1081705

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1081707

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.437

High

1081709

NIN
Ninein

1

19

High-throughput

0.437

High

1081712

BICD1
Protein bicaudal D homolog 1

1

19

High-throughput

0.437

High

1081716

LZTS2
Leucine zipper putative tumor suppressor 2

1

19

High-throughput

0.437

High

1081702

S39A5
Zinc transporter ZIP5

1

7

High-throughput

0.407

High

1081706

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

1081708

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.407

High

1081713

S39AD
Zinc transporter ZIP13

1

7

High-throughput

0.407

High

687981

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.269

Low

612204

ARF4
ADP-ribosylation factor 4

1

0

High-throughput

0.249

Low

1081704

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1081710

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.232

Low

1081714

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.232

Low

1081715

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025