HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	25416956, 33961781
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 345
+	Hs
		280610 KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53		CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06
+	Hs
		359390 K1C14_HUMAN (87-400): 4.31e-146: 425: 53.82		CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50
+	Hs
		1149377 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		724787 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		725143 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Hs
		1055225 KRT81_HUMAN (4-426): 1.43e-90: 285: 27.65		MYO10_HUMAN (36-324): 1.73e-29: 121: 15.92
+	Hs
		943698 KRT85_HUMAN (1-428): 1.82e-88: 279: 26.62		MYO10_HUMAN (36-324): 1.73e-29: 121: 15.92