HitPredict

Interactor 1: NXN (Q6DKJ4)
Nucleoredoxin (EC 1.8.1.8)
Gene: NXN

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 716
+	Mm
		956261 NXN_MOUSE (1-435): 0: 666: 97.93		DVL3_MOUSE (1-716): 4.23e-172: 512: 99.02
+	Mm
		844411 NXN_MOUSE (1-435): 0: 666: 97.93		DVL1_MOUSE (1-716): 3.66e-157: 473: 62.83
+	Hs
		150719 NXN_HUMAN (1-435): 0: 666: 100.00		DVL1_HUMAN (1-716): 8.84e-151: 456: 63.66
+	Mm
		956260 NXN_MOUSE (1-435): 0: 666: 97.93		DVL2_MOUSE (3-716): 2.64e-136: 420: 64.80
+	Hs
		151039 NXN_HUMAN (1-435): 0: 666: 100.00		DVL2_HUMAN (3-716): 2.33e-133: 412: 65.13