HitPredict

Interactor 1: Q6FGM0 (Q6FGM0)
Endophilin-A2 (Endophilin-2)
Gene: SH3GL1

Interactor 2: Q8IZ09 (Q8IZ09)
SH3GL2 protein
Gene: SH3GL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAR~BAR
Common GO terms	GO:0016191 - synaptic vesicle uncoating GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 368 Hs			1 279
+	Hs
		1307414 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		SH3G2_HUMAN (1-279): 7.44e-124: 358: 99.64
+	Hs
		1307430 SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30		SH3G2_HUMAN (1-279): 7.44e-124: 358: 99.64
+	Hs
		1151009 Q6FGM0_HUMAN (1-368): 7.32e-90: 276: 100.00		Q6FGM0_HUMAN (1-277): 2.92e-119: 347: 74.73
+	Hs
		1307413 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		SH3G1_HUMAN (1-277): 2.92e-119: 347: 74.73
+	Hs
		1307429 SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75		SH3G2_HUMAN (1-279): 7.44e-124: 358: 99.64
+	Mm
		1143920 SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02		SH3G2_MOUSE (1-279): 1.77e-122: 355: 98.93
+	Hs
		1307415 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		SH3G3_HUMAN (1-260): 4.29e-116: 339: 68.85
+	Hs
		1307446 SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30		SH3G3_HUMAN (1-260): 4.29e-116: 339: 68.85
+	Dm
		1249969 SH3G3_DROME (1-367): 1.34e-75: 239: 48.10		SH3G3_DROME (1-258): 1.36e-97: 292: 52.12
+	Hs
		1377531 SHLB1_HUMAN (10-363): 3.1e-69: 223: 25.28		SHLB1_HUMAN (10-277): 5.09e-95: 285: 25.63
+	Hs
		1344263 SHLB1_HUMAN (10-363): 3.1e-69: 223: 25.28		SHLB2_HUMAN (10-273): 6.95e-85: 261: 22.59
+	Hs
		1148391 SHLB1_HUMAN (10-363): 3.1e-69: 223: 25.28		RHG17_HUMAN (6-251): 2.45e-77: 253: 21.97
+	Hs
		1344251 SHLB2_HUMAN (10-363): 1.2e-58: 196: 22.39		SHLB2_HUMAN (10-273): 6.95e-85: 261: 22.59
+	Hs
		1089302 RHG44_HUMAN (6-251): 8.5e-47: 172: 22.22		RHG17_HUMAN (6-251): 2.45e-77: 253: 21.97
+	Dm
		1249959 Q8T389_DROME (2-365): 2.52e-50: 174: 21.32		Q8T389_DROME (10-274): 1.45e-80: 249: 24.54
+	Dm
		1249175 Q8T389_DROME (2-365): 2.52e-50: 174: 21.32		Q8SYD9_DROME (10-274): 2.97e-78: 243: 23.51