HitPredict

Interactor 1: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 136
+	Hs
		934877 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		391649 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		470336 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086182 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		935170 H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086192 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174619 H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		391723 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		470399 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1086293 H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		391655 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		391757 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		470350 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		470427 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		1174640 H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		391740 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		H37_HUMAN (1-136): 3.26e-59: 181: 97.06
+	Hs
		470413 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		H37_HUMAN (1-136): 3.26e-59: 181: 97.06
+	Hs
		1157222 H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		391597 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		594830 H2A1D_HUMAN (1-130): 7.72e-67: 199: 97.69		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00