HitPredict

Interactor 1: Q6GQ04 (Q6GQ04)
Cell division cycle protein 27 homolog
Gene: MGC80529

Interactor 2: Q7T0N9 (Q7T0N9)
Cell division cycle 23 L homeolog (MGC69122 protein)
Gene: cdc23.L

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	24770399, 20951947
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC3~TPR_11, ANAPC3~TPR_8, TPR_1~TPR_11, TPR_1~TPR_8, TPR_11~TPR_8, TPR_8~TPR_8
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 833 Xl			1 580
+	Hs
		672916 CDC27_HUMAN (1-833): 0: 553: 89.33		CDC23_HUMAN (2-580): 5.4e-107: 335: 88.26
+	Xl
		1151586 Q6GQ04_XENLA (1-833): 0: 568: 100.00		Q8AVF0_XENLA (61-580): 1.42e-94: 300: 98.46
+	Xl
		1150214 Q6GQ04_XENLA (1-833): 0: 568: 100.00		Q6DDX5_XENLA (32-548): 1.4e-55: 198: 15.49
+	Hs
		672917 CDC27_HUMAN (1-833): 0: 553: 89.33		APC7_HUMAN (148-553): 9.37e-24: 107: 12.02
+	Mm
		56872 CDC27_MOUSE (1-833): 0: 549: 88.85		APC7_MOUSE (148-553): 3.05e-22: 102: 12.25
+	Hs
		672772 CDC27_HUMAN (1-833): 0: 553: 89.33		CDC27_HUMAN (25-309): 7.93e-17: 86.4: 14.29
+	Xl
		1150241 Q6GQ04_XENLA (1-833): 0: 568: 100.00		Q6DFI7_XENLA (2-353): 5.08e-09: 61: 10.62
+	Hs
		672822 CDC27_HUMAN (1-833): 0: 553: 89.33		CDC16_HUMAN (2-353): 3.78e-09: 61.4: 10.34
+	Hs
		1356109 APC7_HUMAN (309-822): 2.98e-65: 230: 15.92		CDC23_HUMAN (2-580): 5.4e-107: 335: 88.26
+	Sc
		561118 CDC27_YEAST (2-717): 1.03e-75: 263: 16.51		CDC23_YEAST (11-539): 2.68e-55: 199: 27.14
+	Sc
		454909 CDC27_YEAST (2-717): 1.03e-75: 263: 16.51		CDC16_YEAST (13-571): 3.46e-52: 193: 15.70
+	Hs
		174451 OGT1_HUMAN (323-801): 9.48e-76: 268: 13.15		OGT1_HUMAN (282-577): 8.86e-43: 166: 15.88
+	Hs
		175291 OGT1_HUMAN (323-801): 9.48e-76: 268: 13.15		APC7_HUMAN (148-553): 9.37e-24: 107: 12.02
+	Sc
		743211 CDC27_YEAST (2-717): 1.03e-75: 263: 16.51		CDC27_YEAST (381-577): 1.2e-09: 63.3: 11.44
+	Hs
		1022909 Q4KMX6_HUMAN (309-822): 3.1e-65: 230: 15.92		CDC16_HUMAN (2-353): 3.78e-09: 61.4: 10.34
+	Hs
		1023016 APC7_HUMAN (309-822): 2.98e-65: 230: 15.92		CDC16_HUMAN (2-353): 3.78e-09: 61.4: 10.34