Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: RRAGD (Q9NQL2)
Ras-related GTP-binding protein D (Rag D) (RagD) (EC 3.6.5.-)
Gene: RRAGD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 34079125, 33961781, 20381137, 22424946, 25561175
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gtr1_RagA~LAMTOR
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0008104 - protein localization
GO:0032008 - positive regulation of TOR signaling
GO:0051020 - GTPase binding
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 161
Hs

1 400
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024