HitPredict

Interactor 1: TWF2 (Q6IBS0)
Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein)
Gene: TWF2

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045296 - cadherin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 349 Hs			1 1116
+	Hs
		724875 TWF2_HUMAN (1-349): 1.13e-170: 480: 100.00		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		724797 TWF1_HUMAN (1-344): 4.14e-154: 438: 65.41		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		1016503 TWF1_HUMAN (1-344): 4.14e-154: 438: 65.41		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Hs
		724739 DEST_HUMAN (3-138): 2.92e-40: 141: 21.29		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		725077 COF2_HUMAN (3-138): 6.86e-35: 127: 21.80		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		618006 COF1_HUMAN (3-138): 3.06e-32: 120: 17.95		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		149440 COF2_HUMAN (3-138): 6.86e-35: 127: 21.80		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		148406 COF1_HUMAN (3-138): 3.06e-32: 120: 17.95		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		894675 DEST_HUMAN (3-138): 2.92e-40: 141: 21.29		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Hs
		1268120 COF2_HUMAN (3-138): 6.86e-35: 127: 21.80		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Hs
		618142 COF1_HUMAN (3-138): 3.06e-32: 120: 17.95		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73