Protein: RS5
Small ribosomal subunit protein uS7 (40S ribosomal protein S5) (RP14) (S2) (YS8)

Gene: RS5, RPS5
Organism: Saccharomyces cerevisiae S288C
Interactions: 204
UniProt ID: P26783

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0000054 - ribosomal subunit export from nucleus
GO:0002181 - cytoplasmic translation
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

688901

RIO2
Serine/threonine-protein kinase RIO2

9

3

Small-scale

0.962

High

441745

RS14A
Small ribosomal subunit protein uS11A

3

3

High-throughput

0.827

High

688966

RS25A
Small ribosomal subunit protein eS25A

3

3

Small-scale

0.827

High

454916

RS19A
Small ribosomal subunit protein eS19A

2

2

High-throughput

0.754

High

688961

RIO1
Serine/threonine-protein kinase RIO1

2

3

High-throughput

0.754

High

688872

ENP1
Essential nuclear protein 1

6

1

Small-scale

0.721

High

688867

GBLP
Small ribosomal subunit protein RACK1

5

6

Small-scale

0.702

High

678364

PWP2
Periodic tryptophan protein 2

4

2

Small-scale

0.694

High

392332

HSP82
ATP-dependent molecular chaperone HSP82

4

2

High-throughput

0.676

High

677304

KRR1
KRR1 small subunit processome component

3

2

Small-scale

0.656

High

688856

RS3A1
Small ribosomal subunit protein eS1A

3

2

Small-scale

0.640

High

688898

IMB4
Importin subunit beta-4

2

2

Small-scale

0.628

High

688948

RRP9
Ribosomal RNA-processing protein 9

2

7

High-throughput

0.628

High

585684

UBC4
Ubiquitin-conjugating enzyme E2 4

3

0

Small-scale

0.627

High

455382

RS19B
Small ribosomal subunit protein eS19B

1

2

High-throughput

0.618

High

502633

RS25B
Small ribosomal subunit protein eS25B

1

3

High-throughput

0.618

High

503473

RS28B
Small ribosomal subunit protein eS28B

1

2

High-throughput

0.618

High

514109

RS16B
Small ribosomal subunit protein uS9B

1

6

High-throughput

0.618

High

688890

RS14B
Small ribosomal subunit protein uS11B

1

3

High-throughput

0.618

High

688967

RS28A
Small ribosomal subunit protein eS28A

1

2

High-throughput

0.618

High

558608

CAF20
Cap-associated protein CAF20

3

0

Small-scale

0.613

High

688914

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

0

Small-scale

0.613

High

688949

NOC4
Nucleolar complex protein 4

3

0

Small-scale

0.613

High

688950

TSR1
Ribosome biogenesis protein TSR1

2

1

High-throughput

0.611

High

688884

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.602

High

688928

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.602

High

678225

BUD23
18S rRNA

1

0

High-throughput

0.586

High

517924

SSBP1
Single-stranded nucleic acid-binding protein

2

1

High-throughput

0.585

High

149623

RS9A
Small ribosomal subunit protein uS4A

2

3

High-throughput

0.584

High

383555

RS17A
Small ribosomal subunit protein eS17A

2

2

High-throughput

0.584

High

434877

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.584

High

512296

RS6A
Small ribosomal subunit protein eS6A

2

4

High-throughput

0.584

High

512858

RS8A
Small ribosomal subunit protein eS8A

2

2

High-throughput

0.584

High

674455

RS2
Small ribosomal subunit protein uS5

2

6

High-throughput

0.584

High

688832

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.584

High

688852

RSSA1
Small ribosomal subunit protein uS2A

2

8

High-throughput

0.584

High

688874

RS20
Small ribosomal subunit protein uS10

2

1

High-throughput

0.584

High

688940

RS15
Small ribosomal subunit protein uS19

2

3

High-throughput

0.584

High

688943

DHR1
Probable ATP-dependent RNA helicase DHR1

2

2

High-throughput

0.584

High

670401

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

688865

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.576

High

364370

CDK1
Cyclin-dependent kinase 1

2

1

High-throughput

0.571

High

554671

YPK1
Serine/threonine-protein kinase YPK1

1

3

Small-scale

0.561

High

435813

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.559

High

688885

RPN10
26S proteasome regulatory subunit RPN10

2

0

Small-scale

0.559

High

688919

RS12
Small ribosomal subunit protein eS12

2

0

High-throughput

0.559

High

688839

HRR25
Casein kinase I homolog HRR25

2

0

Small-scale

0.547

High

438631

SC160
Protein SCP160

1

3

High-throughput

0.536

High

688836

URA7
CTP synthase 1

1

2

High-throughput

0.536

High

688842

XPO1
Exportin-1

1

2

High-throughput

0.536

High

688849

ZUO1
Zuotin

1

3

High-throughput

0.536

High

688875

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

688881

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.536

High

688893

IF2P
Eukaryotic translation initiation factor 5B

1

5

High-throughput

0.536

High

688932

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

688938

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

688944

UTP15
U3 small nucleolar RNA-associated protein 15

1

5

High-throughput

0.536

High

417042

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.513

High

452484

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.513

High

454334

PHO2
Regulatory protein PHO2

1

0

High-throughput

0.513

High

454414

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

460954

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

688873

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.513

High

688906

FAF1
Protein FAF1

1

0

Small-scale

0.513

High

688912

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

688918

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

Small-scale

0.506

High

617931

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

3

Small-scale

0.501

High

665784

KPC1
Protein kinase C-like 1

1

2

Small-scale

0.501

High

438393

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.489

High

609041

SKI3
Superkiller protein 3

1

1

High-throughput

0.489

High

688896

BIM1
Protein BIM1

1

1

High-throughput

0.489

High

688904

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

688942

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

2

High-throughput

0.489

High

382843

RMAR
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

409969

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

433488

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

435526

RS9B
Small ribosomal subunit protein uS4B

1

3

High-throughput

0.479

High

436339

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

3

High-throughput

0.479

High

502709

RS21A
Small ribosomal subunit protein eS21A

1

1

High-throughput

0.479

High

502886

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

504072

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

512028

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

513335

RL23B
Large ribosomal subunit protein uL14B

1

1

High-throughput

0.479

High

514493

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

544014

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.479

High

570218

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.479

High

578954

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

655403

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.479

High

677017

GID7
GID complex subunit 7

1

3

High-throughput

0.479

High

679433

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

682178

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

688840

MCM4
DNA replication licensing factor MCM4

1

3

High-throughput

0.479

High

688843

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

688844

SYKM
Lysine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

688847

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

688853

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

688859

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

688869

MCM7
DNA replication licensing factor MCM7

1

2

High-throughput

0.479

High

688870

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

High-throughput

0.479

High

688876

RS27B
Small ribosomal subunit protein eS27B

1

1

High-throughput

0.479

High

688878

ECM29
Proteasome component ECM29

1

2

High-throughput

0.479

High

688891

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

688894

RS26A
Small ribosomal subunit protein eS26A

1

1

High-throughput

0.479

High

688895

RS26B
Small ribosomal subunit protein eS26B

1

1

High-throughput

0.479

High

688909

RLP7
Ribosome biogenesis protein RLP7

1

3

High-throughput

0.479

High

688910

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.479

High

688911

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.479

High

688915

RSSA2
Small ribosomal subunit protein uS2B

1

8

High-throughput

0.479

High

688917

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.479

High

688923

VID30
GID complex subunit 1

1

1

High-throughput

0.479

High

688924

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.479

High

688933

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

688939

NOP3
Serine/arginine

1

7

High-throughput

0.479

High

688941

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.479

High

688958

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

688965

RS21B
Small ribosomal subunit protein eS21B

1

1

High-throughput

0.479

High

481978

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

511742

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.458

High

557568

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

0

High-throughput

0.458

High

666403

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

688846

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

688857

LTV1
Protein LTV1

1

0

High-throughput

0.458

High

688862

EAP1
Protein EAP1

1

0

High-throughput

0.458

High

688863

YKH1
Uncharacterized oxidoreductase YKL071W

1

0

High-throughput

0.458

High

688864

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

688871

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

688879

OTU2
OTU domain-containing protein 2

1

0

High-throughput

0.458

High

688880

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

688889

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

688892

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

688913

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

688921

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.458

High

688922

DXO
Decapping nuclease RAI1

1

0

Small-scale

0.458

High

688926

SLX9
Ribosome biogenesis protein SLX9

1

0

Small-scale

0.458

High

688927

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

688929

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

688930

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

Small-scale

0.458

High

688931

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

688934

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

688945

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

688953

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

Small-scale

0.458

High

688954

SGO1
Shugoshin

1

0

High-throughput

0.458

High

688955

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

394296

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

509432

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

High-throughput

0.445

High

523224

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

584191

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

2

High-throughput

0.445

High

688833

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.445

High

688834

NAM9
Small ribosomal subunit protein uS4m

1

1

High-throughput

0.445

High

688841

RENT1
ATP-dependent helicase NAM7

1

1

High-throughput

0.445

High

688848

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.445

High

688900

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

401909

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.437

High

688838

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

688854

IXR1
Intrastrand cross-link recognition protein

1

4

Small-scale

0.437

High

688903

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

688905

ULP2
Ubiquitin-like-specific protease 2

1

1

Small-scale

0.437

High

688920

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

688937

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

688956

NAT5
N-alpha-acetyltransferase NAT5

1

1

High-throughput

0.437

High

688963

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.437

High

478395

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

High-throughput

0.426

High

688851

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.426

High

688858

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.426

High

688860

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.426

High

688868

CDC27
Anaphase-promoting complex subunit CDC27

1

0

High-throughput

0.426

High

688883

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

688886

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.426

High

688902

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.426

High

688925

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.426

High

688957

GPN2
GPN-loop GTPase 2

1

0

High-throughput

0.426

High

381911

H4
Histone H4

1

1

High-throughput

0.407

High

688845

BTAF1
TATA-binding protein-associated factor MOT1

1

2

High-throughput

0.407

High

688908

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

638785

REB1
DNA-binding protein REB1

1

0

High-throughput

0.279

Low

688835

FUN19
SWIRM domain-containing protein FUN19

1

0

High-throughput

0.279

Low

688964

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

688952

SNA4
Protein SNA4

1

0

Small-scale

0.261

Low

456512

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

High-throughput

0.249

Low

661465

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

688837

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

688850

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

688866

YC16
UPF0743 protein YCR087C-A

1

0

High-throughput

0.249

Low

688877

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

688888

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

688899

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.249

Low

688907

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

688916

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

688935

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

688936

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

688946

TMA64
Translation machinery-associated protein 64

1

0

High-throughput

0.249

Low

688959

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

688960

YD157
Uncharacterized protein YDL157C, mitochondrial

1

0

Small-scale

0.249

Low

688962

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low

416799

DNLI1
DNA ligase 1

1

0

High-throughput

0.232

Low

456351

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

554404

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

High-throughput

0.232

Low

688855

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.232

Low

688861

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.232

Low

688882

RPF1
Ribosome production factor 1

1

0

High-throughput

0.232

Low

688887

SUR2
Sphingolipid C4-hydroxylase SUR2

1

0

High-throughput

0.232

Low

688897

PIC2
Mitochondrial phosphate carrier protein 2

1

0

High-throughput

0.232

Low

688947

ERP1
Protein ERP1

1

0

High-throughput

0.232

Low

688951

RXT3
Transcriptional regulatory protein RXT3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025