HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: CRACD (Q6ZU35)
Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics)
Gene: CRACD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Hs			1 1233
+	Hs
		724876 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		551742 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		DESP_HUMAN (71-540): 1.63e-15: 84.6: 16.42
+	Hs
		547100 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		1051468 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		1313532 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		CP250_HUMAN (109-757): 1.05e-22: 108: 10.54
+	Hs
		1068669 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		PLEC_HUMAN (69-693): 1.83e-11: 71.2: 10.88
+	Hs
		547222 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		1051472 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		125451 WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		725200 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		MYH10_HUMAN (149-782): 1.39e-23: 110: 9.39
+	Hs
		724914 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		1336100 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		DAPLE_HUMAN (45-776): 8.72e-20: 98.5: 8.09
+	Hs
		148941 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		149443 PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		876522 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		DAPLE_HUMAN (45-776): 8.72e-20: 98.5: 8.09
+	Hs
		876370 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		CGNL1_HUMAN (4-509): 3.23e-19: 96.2: 12.48
+	Hs
		551845 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		DESP_HUMAN (71-540): 1.63e-15: 84.6: 16.42
+	Hs
		547136 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		1061257 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		NUMA1_HUMAN (354-775): 5.31e-10: 66.2: 10.75
+	Hs
		125464 WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39		NUMA1_HUMAN (354-775): 5.31e-10: 66.2: 10.75