HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: KSR1 (Q8IVT5)
Kinase suppressor of Ras 1 (EC 2.7.11.1)
Gene: KSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Hs			1 923
+	Hs
		1217987 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		KSR1_HUMAN (1-923): 0: 765: 100.00
+	Hs
		876434 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		KSR1_HUMAN (1-923): 0: 765: 100.00
+	Hs
		411764 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		665661 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		EPHB2_HUMAN (223-895): 5.19e-149: 469: 14.82
+	Hs
		872491 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		EPHA5_HUMAN (223-888): 4.57e-149: 469: 14.15
+	Hs
		1072602 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		EPHA7_HUMAN (215-914): 9.83e-149: 467: 14.59
+	Hs
		600673 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72
+	Hs
		600712 PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16		EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72
+	Hs
		411861 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		665569 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		EPHB2_HUMAN (223-895): 5.19e-149: 469: 14.82
+	Hs
		876391 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		EPHA7_HUMAN (215-914): 9.83e-149: 467: 14.59
+	Hs
		542919 SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18		BRAF_HUMAN (252-914): 2.03e-148: 459: 22.80
+	Hs
		665186 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62
+	Hs
		125134 WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39		BRAF_HUMAN (252-914): 2.03e-148: 459: 22.80
+	Hs
		600674 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72
+	Hs
		872402 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		EPHB3_HUMAN (193-914): 1.2e-139: 443: 15.58
+	Hs
		374608 CNKR2_HUMAN (119-516): 1.33e-45: 181: 17.65		RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03
+	Hs
		125075 WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39		RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03
+	Hs
		411897 PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		411864 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59