HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	27173435, 28877994
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Hs			1 759
+	Hs
		1334851 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1231364 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		876531 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1331555 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1153287 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150593 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		1059994 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00
+	Hs
		1154080 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		LHX3_HUMAN (369-635): 7e-43: 162: 14.44
+	Hs
		1186090 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		1082190 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		CSRP2_HUMAN (254-450): 3.35e-41: 151: 18.27
+	Hs
		876416 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		ABLM2_HUMAN (369-647): 1.72e-22: 104: 11.79
+	Hs
		597776 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		CSRP1_HUMAN (254-449): 3.7e-34: 131: 15.82
+	Hs
		1082184 NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47		CSRP2_HUMAN (254-450): 3.35e-41: 151: 18.27
+	Hs
		1056876 MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		1056843 MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84		CSRP2_HUMAN (254-450): 3.35e-41: 151: 18.27
+	Hs
		1060064 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00
+	Hs
		200184 NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47		TGFI1_HUMAN (263-447): 1.47e-16: 85: 15.64
+	Hs
		200183 ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49		TGFI1_HUMAN (263-447): 1.47e-16: 85: 15.64
+	Mm
		1143674 ITCH_MOUSE (43-213): 6.22e-16: 85.1: 17.05		TGFI1_MOUSE (263-447): 3.65e-15: 80.8: 16.90
+	Hs
		1060073 WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00