HitPredict

Interactor 1: LAIR2 (Q6ISS4)
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) (CD antigen CD306)
Gene: LAIR2

Interactor 2: COHA1 (Q9UMD9)
Collagen alpha-1(XVII) chain (180 kDa bullous pemphigoid antigen 2) (Bullous pemphigoid antigen 2) [Cleaved into: 120 kDa linear IgA disease antigen (120 kDa linear IgA dermatosis antigen) (Linear IgA disease antigen 1) (LAD-1); 97 kDa linear IgA disease antigen (97 kDa linear IgA bullous dermatosis antigen) (97 kDa LAD antigen) (97-LAD) (Linear IgA bullous disease antigen of 97 kDa) (LABD97)]
Gene: COL17A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 1497
+	Hs
		358663 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO4A1_HUMAN (384-882): 2.54e-50: 198: 26.22
+	Hs
		358527 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO1A1_HUMAN (856-1496): 6.44e-48: 190: 22.87
+	Hs
		358526 LAIR1_HUMAN (1-141): 1.84e-52: 169: 81.56		CO1A1_HUMAN (856-1496): 6.44e-48: 190: 22.87
+	Hs
		358611 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO2A1_HUMAN (366-701): 5.87e-30: 131: 24.04
+	Hs
		1047980 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO4A6_HUMAN (366-728): 7.18e-29: 128: 23.63
+	Hs
		441068 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO4A2_HUMAN (367-728): 9.78e-28: 124: 24.59
+	Hs
		409733 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO5A2_HUMAN (1124-1495): 1.17e-25: 118: 16.26
+	Hs
		518053 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO6A3_HUMAN (1383-1497): 2.87e-23: 110: 28.93
+	Hs
		596163 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO5A1_HUMAN (389-887): 1.03e-21: 105: 27.18
+	Hs
		358637 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO3A1_HUMAN (1167-1495): 7.19e-21: 102: 17.73
+	Hs
		358515 KI3S1_HUMAN (17-139): 1.65e-21: 90.5: 23.81		CO1A1_HUMAN (856-1496): 6.44e-48: 190: 22.87
+	Hs
		518008 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO6A2_HUMAN (815-1045): 9.49e-19: 95.1: 32.73
+	Hs
		862504 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO4A4_HUMAN (1067-1485): 1.02e-16: 88.8: 18.12
+	Hs
		517953 LAIR2_HUMAN (1-152): 8.02e-60: 183: 100.00		CO6A1_HUMAN (784-1046): 9.45e-12: 72: 37.12
+	Hs
		358614 OSCAR_HUMAN (15-137): 1.95e-13: 67.3: 23.70		CO2A1_HUMAN (366-701): 5.87e-30: 131: 24.04