HitPredict

Interactor 1: NEDD8 (Q15843)
Ubiquitin-like protein NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8)
Gene: NEDD8

Interactor 2: H3C (Q6NXT2)
Histone H3.3C (Histone H3.5)
Gene: H3-5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 135
+	Hs
		987075 RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14		H3C_HUMAN (1-135): 9.3e-59: 179: 100.00
+	Hs
		986980 RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14		H31_HUMAN (1-135): 5.13e-58: 177: 92.65
+	Hs
		986988 RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14		H33_HUMAN (1-135): 2.2e-57: 176: 94.85
+	Hs
		987050 RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14		H31T_HUMAN (1-135): 2.71e-57: 176: 89.71
+	Hs
		987086 RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14		H32_HUMAN (1-135): 8.76e-57: 174: 93.38
+	Hs
		987385 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		H3C_HUMAN (1-135): 9.3e-59: 179: 100.00
+	Hs
		987321 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		H31_HUMAN (1-135): 5.13e-58: 177: 92.65
+	Hs
		987326 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		H33_HUMAN (1-135): 2.2e-57: 176: 94.85
+	Hs
		987371 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		H31T_HUMAN (1-135): 2.71e-57: 176: 89.71
+	Hs
		507234 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		H3C_HUMAN (1-135): 9.3e-59: 179: 100.00
+	Hs
		987390 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		H32_HUMAN (1-135): 8.76e-57: 174: 93.38
+	Hs
		507154 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		H31_HUMAN (1-135): 5.13e-58: 177: 92.65
+	Hs
		507159 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		H33_HUMAN (1-135): 2.2e-57: 176: 94.85
+	Hs
		507210 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		H31T_HUMAN (1-135): 2.71e-57: 176: 89.71
+	Hs
		507246 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		H32_HUMAN (1-135): 8.76e-57: 174: 93.38
+	Hs
		998358 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		H31_HUMAN (1-135): 5.13e-58: 177: 92.65
+	Hs
		1016891 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		H33_HUMAN (1-135): 2.2e-57: 176: 94.85
+	Hs
		1154837 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		H31T_HUMAN (1-135): 2.71e-57: 176: 89.71
+	Hs
		1154859 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		H32_HUMAN (1-135): 8.76e-57: 174: 93.38