HitPredict

Interactor 1: Q6NS03 (Q6NS03)
Exportin 1 S homeolog (Xpo1 protein)
Gene: xpo1.S

Interactor 2: PAB2A (Q9DDY9)
Polyadenylate-binding protein 2-A (PABP-2-A) (Poly(A)-binding protein 2-A) (Nuclear poly(A)-binding protein 1-A) (Poly(A)-binding protein II-A) (PABII-A) (Polyadenylate-binding nuclear protein 1-A) (XLnPABP2-A) (nPABP2-A) (xPABPII-A)
Gene: pabpn1-a

Species: Xenopus laevis

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~Xpo1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1071 Xl			1 296
+	Hs
		162812 XPO1_HUMAN (1-1071): 0: 1003: 97.01		PAP1L_HUMAN (154-275): 1.1e-22: 99.5: 15.45
+	Hs
		162372 XPO1_HUMAN (1-1071): 0: 1003: 97.01		PABP1_HUMAN (154-275): 2e-21: 96.1: 13.82
+	Hs
		162702 XPO1_HUMAN (1-1071): 0: 1003: 97.01		PABP4_HUMAN (154-275): 3.05e-21: 95.7: 15.45
+	Xl
		1155766 Q6NS03_XENLA (1-1071): 0: 1003: 100.00		EPABA_XENLA (164-275): 4.22e-20: 92.2: 15.93
+	Xl
		1122650 Q6NS03_XENLA (1-1071): 0: 1003: 100.00		Q569S7_XENLA (63-272): 1.34e-14: 75.2: 14.91
+	Sc
		676127 XPO1_YEAST (14-1067): 0: 830: 46.54		SGN1_YEAST (83-296): 1.78e-38: 137: 25.00
+	Sc
		376677 XPO1_YEAST (14-1067): 0: 830: 46.54		PABP_YEAST (134-274): 5e-19: 88.7: 18.31
+	Sc
		676427 XPO1_YEAST (14-1067): 0: 830: 46.54		NOP12_YEAST (159-263): 9.98e-17: 81.7: 30.08
+	Hs
		1199029 TNPO1_HUMAN (33-1044): 1.07e-142: 452: 13.40		PABP2_HUMAN (100-296): 1.15e-40: 144: 92.42
+	Sp
		145478 YNR7_SCHPO (26-876): 1.91e-92: 318: 14.14		PAB2_SCHPO (104-246): 6.03e-45: 151: 49.65
+	Sp
		144309 IMB2_SCHPO (21-1048): 3.59e-92: 316: 12.67		PAB2_SCHPO (104-246): 6.03e-45: 151: 49.65