Interactor 1: LRC8E (Q6NSJ5)
Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E)
Gene: LRRC8E

Interactor 2: LRC8B (Q6P9F7)
Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)
Gene: LRRC8B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_5, LRR_1~LRR_8, LRR_5~LRR_8, LRR_8~LRR_8, Pannexin_like~Pannexin_like
Common GO terms GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0015810 - aspartate transmembrane transport
GO:0034702 - monoatomic ion channel complex
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 796
Hs

1 803
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024