HitPredict

Interactor 1: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030139 - endocytic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 908 Hs			1 665
+	Hs
		1251883 RIN3_HUMAN (1-908): 0: 597: 89.04		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1251962 RIN3_HUMAN (1-908): 0: 597: 89.04		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		557717 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		1155937 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		1078842 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		1136527 RIN3_HUMAN (1-908): 0: 597: 89.04		SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72
+	Hs
		557745 RIN3_HUMAN (1-908): 0: 597: 89.04		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		69536 RIN3_HUMAN (1-908): 0: 597: 89.04		B0LPF3_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924717 RIN3_HUMAN (1-908): 0: 597: 89.04		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		70370 RIN3_HUMAN (1-908): 0: 597: 89.04		B2R6S4_HUMAN (104-396): 1.46e-29: 122: 16.88
+	Hs
		1251932 RIN3_HUMAN (1-908): 0: 597: 89.04		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		275213 RIN3_HUMAN (1-908): 0: 597: 89.04		GRAP2_HUMAN (1-56): 2.18e-17: 85.8: 32.14
+	Hs
		1167810 RIN3_HUMAN (1-908): 0: 597: 89.04		DNMBP_HUMAN (104-607): 3.03e-16: 85.1: 15.82
+	Hs
		235552 RIN3_HUMAN (1-908): 0: 597: 89.04		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Hs
		924632 TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		1044770 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Rn
		192744 SYNJ1_RAT (153-642): 1.6e-44: 177: 15.79		SRBS2_RAT (3-155): 3.11e-11: 68.9: 30.25
+	Hs
		235502 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Hs
		1044784 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		SH3R1_HUMAN (241-599): 5.37e-12: 71.2: 13.28
+	Hs
		235523 TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82