Interactor 1: ANM5 (Q6NUA1)
Protein arginine N-methyltransferase 5 (prmt5) (EC 2.1.1.320) (Histone synthetic lethal 7 protein) (Hsl7) (Histone-arginine N-methyltransferase PRMT5)
Gene: prmt5

Interactor 2: MEP50 (Q6NUD0)
Methylosome protein WDR77 (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77)
Gene: wdr77

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 23451136
Identification Methods x-ray crystallography, molecular sieving, static light scattering, cosedimentation in solution, x ray scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PRMT5_TIM~WD40
Common GO terms GO:0005829 - cytosol
GO:0034709 - methylosome
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 633
Xl

1 333
+ Xl
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024