HitPredict

Interactor 1: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Interactor 2: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	34079125, 33961781, 28514442
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 779
+	Hs
		1157352 JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00		PRP16_HUMAN (2-778): 0: 752: 34.78
+	Hs
		1055395 JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00		DHX8_HUMAN (45-733): 0: 731: 41.51
+	Hs
		1220315 PHF8_HUMAN (1-326): 9.44e-83: 275: 17.12		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		256420 PHF2_HUMAN (5-326): 1.88e-74: 252: 16.92		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Sp
		293771 JHD1_SCHPO (2-332): 1.45e-51: 187: 14.37		PRH1_SCHPO (48-699): 0: 762: 38.07
+	Sp
		293811 JHD1_SCHPO (2-332): 1.45e-51: 187: 14.37		PRP16_SCHPO (2-765): 0: 729: 36.08
+	Sp
		194924 JHD1_SCHPO (2-332): 1.45e-51: 187: 14.37		DHX15_SCHPO (7-731): 0: 703: 36.61