HitPredict

Interactor 1: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 245
+	Hs
		1157408 JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		1261312 PHF8_HUMAN (1-326): 9.44e-83: 275: 17.12		RN138_HUMAN (1-245): 6.92e-57: 183: 100.00
+	Hs
		1019385 PHF8_HUMAN (1-326): 9.44e-83: 275: 17.12		TRI26_HUMAN (4-239): 2.73e-33: 127: 15.64
+	Mm
		1158239 KDM2B_MOUSE (2-313): 8.78e-72: 246: 18.10		RING2_MOUSE (2-188): 1.78e-28: 112: 18.72
+	Hs
		1245587 KDM2B_HUMAN (10-369): 1.42e-69: 240: 17.69		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Mm
		193408 KDM2B_MOUSE (2-313): 8.78e-72: 246: 18.10		RING1_MOUSE (2-74): 1.86e-21: 93.9: 27.40
+	Hs
		987996 KDM2B_HUMAN (10-369): 1.42e-69: 240: 17.69		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Dm
		1361711 JHD1_DROME (2-294): 8.22e-65: 226: 15.43		RING1_DROME (2-75): 5.14e-21: 92.7: 27.03