HitPredict

Interactor 1: M9PGB1 (M9PGB1)
Rho-type guanine nucleotide exchange factor, isoform G
Gene: RtGEF

Interactor 2: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25484297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 923 Dm			1 669
+	Dm
		115760 M9PGB1_DROME (1-923): 0: 960: 100.00		PAK_DROME (17-314): 9.61e-114: 359: 36.89
+	Dm
		1367664 Q9VIN1_DROME (1-674): 5.96e-147: 452: 93.78		PAK_DROME (17-314): 9.61e-114: 359: 36.89
+	Mm
		1142068 ARHG7_MOUSE (2-690): 1.79e-109: 359: 31.61		PAK3_MOUSE (26-306): 3.99e-115: 358: 40.28
+	Hs
		1026904 ARHG7_HUMAN (2-620): 3.31e-107: 351: 32.56		PAK2_HUMAN (26-317): 5.83e-118: 364: 37.08
+	Mm
		292047 ARHG7_MOUSE (2-690): 1.79e-109: 359: 31.61		PAK1_MOUSE (2-317): 2.13e-114: 355: 35.85
+	Hs
		1026158 ARHG7_HUMAN (2-620): 3.31e-107: 351: 32.56		PAK1_HUMAN (2-317): 1.29e-115: 358: 35.85
+	Hs
		277605 ARHG7_HUMAN (2-620): 3.31e-107: 351: 32.56		PAK3_HUMAN (6-306): 3.15e-115: 358: 37.18
+	Rn
		223052 ARHG7_RAT (2-607): 4.23e-92: 307: 31.94		AKT3_RAT (14-367): 1.04e-131: 398: 20.06
+	Hs
		81635 B7Z6G2_HUMAN (2-607): 6.62e-103: 338: 31.63		PAK2_HUMAN (26-317): 5.83e-118: 364: 37.08
+	Hs
		548689 VAV_HUMAN (14-561): 1.49e-86: 297: 14.79		KPCT_HUMAN (2-354): 2.28e-130: 402: 20.83
+	Mm
		654978 VAV_MOUSE (15-561): 2.37e-82: 285: 14.29		KPCT_MOUSE (2-354): 1.43e-130: 402: 21.39
+	Hs
		681936 ARG28_HUMAN (18-691): 4.07e-79: 283: 12.77		AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06
+	Rn
		660828 RGRF1_RAT (30-681): 4.88e-79: 282: 12.91		AKT3_RAT (14-367): 1.04e-131: 398: 20.06
+	Hs
		1026910 ARHG6_HUMAN (2-523): 4.3e-91: 308: 32.91		PAK2_HUMAN (26-317): 5.83e-118: 364: 37.08
+	Hs
		277606 ITSN1_HUMAN (1-469): 2.78e-88: 311: 17.69		PAK3_HUMAN (6-306): 3.15e-115: 358: 37.18
+	Hs
		1026167 ARHG6_HUMAN (2-523): 4.3e-91: 308: 32.91		PAK1_HUMAN (2-317): 1.29e-115: 358: 35.85
+	Rn
		223051 ARHG7_RAT (2-607): 4.23e-92: 307: 31.94		PAK1_RAT (2-317): 1.1e-115: 359: 35.85
+	Hs
		855832 VAV2_HUMAN (14-560): 4.85e-86: 296: 13.04		STK24_HUMAN (33-316): 5.77e-120: 366: 51.39
+	Hs
		1217590 ITSN2_HUMAN (3-469): 1.76e-84: 299: 18.92		M4K3_HUMAN (38-308): 1.71e-71: 250: 44.25
+	Hs
		1217525 TIAM2_HUMAN (20-604): 1.44e-80: 288: 15.87		TNIK_HUMAN (33-320): 1.39e-62: 228: 41.06