HitPredict

Interactor 1: ZCHC8 (Q6NZY4)
Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8)
Gene: ZCCHC8

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 235
+	Hs
		1157905 ZCHC8_HUMAN (1-707): 0: 1146: 100.00		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		1157890 ZCHC8_HUMAN (1-707): 0: 1146: 100.00		EXOS8_HUMAN (4-234): 4.65e-59: 189: 19.26
+	Hs
		1063728 ZCHC8_HUMAN (1-707): 0: 1146: 100.00		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Hs
		1130026 ZCHC8_HUMAN (1-707): 0: 1146: 100.00		EXOS6_HUMAN (9-228): 2.79e-42: 146: 25.41