Interactor 1: GCK1 (H2L099)
Germinal center kinase 1 (EC 2.7.11.1)
Gene: gck-1
Interactor 2: PDC10 (Q17958)
Programmed cell death protein 10 homolog (Cerebral cavernous malformation protein 3)
Gene: ccm-3
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.912 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25743393, 14704431, 28285997, 18692475, unassigned701 |
| Identification Methods | biochemical, two hybrid, affinity chromatography technology, two hybrid pooling approach |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDC10_C~PDCD10_N, PDCD10_N~PDCD10_N |
| Common GO terms | GO:0005737 - cytoplasm GO:0043547 - positive regulation of GTPase activity GO:0060562 - epithelial tube morphogenesis GO:0098592 - cytoplasmic side of apical plasma membrane GO:1903358 - regulation of Golgi organization and 1 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
