HitPredict

Interactor 1: Q6P2C6 (Q6P2C6)
MLLT6 protein (MLLT6, PHD finger containing) (Protein AF-17)
Gene: MLLT6

Interactor 2: HTF4 (Q99081)
Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4)
Gene: TCF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 682
+	Hs
		876617 AF17_HUMAN (1-293): 2.82e-98: 314: 93.86		HTF4_HUMAN (1-682): 0: 921: 100.00
+	Hs
		319311 BRD1_HUMAN (3-233): 5.53e-70: 237: 35.57		HTF4_HUMAN (1-682): 0: 921: 100.00
+	Hs
		551176 Q6P2C6_HUMAN (1-325): 1.25e-114: 336: 100.00		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		551101 AF17_HUMAN (1-293): 2.82e-98: 314: 93.86		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Mm
		222401 AF10_MOUSE (1-194): 1.5e-84: 277: 88.66		ITF2_MOUSE (2-682): 0: 804: 62.82
+	Hs
		551100 AF10_HUMAN (1-192): 2.6e-85: 279: 89.58		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Mm
		550224 JADE1_MOUSE (3-286): 2.02e-73: 243: 27.52		TFE2_MOUSE (1-682): 0: 732: 49.43
+	Hs
		551573 NSD3_HUMAN (1-269): 1.48e-56: 199: 17.04		TFE2_HUMAN (2-682): 0: 753: 48.93