HitPredict

Interactor 1: EDC4 (Q6P2E9)
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Gene: EDC4

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 626
+	Hs
		903308 EDC4_HUMAN (1-1401): 0: 1319: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		1295405 CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		1281478 MACF1_HUMAN (908-1276): 1.45e-46: 186: 10.59		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		903607 MACF1_HUMAN (908-1276): 1.45e-46: 186: 10.59		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		1246203 CE164_HUMAN (537-1274): 5.04e-10: 66.6: 13.09		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		577699 SON_HUMAN (426-1085): 5.29e-09: 63.2: 11.38		NLE1_HUMAN (181-575): 1.3e-63: 219: 12.70
+	Mm
		903669 KMT2C_MOUSE (445-898): 7.87e-12: 72.8: 12.68		WDR5_MOUSE (435-622): 2.2e-42: 157: 12.23
+	Hs
		903374 KMT2C_HUMAN (433-1018): 2.98e-10: 67.5: 10.44		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		903405 CBP_HUMAN (423-883): 7.13e-10: 66.3: 11.91		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		577684 SON_HUMAN (426-1085): 5.29e-09: 63.2: 11.38		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		997857 CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		997838 CBP_HUMAN (423-883): 7.13e-10: 66.3: 11.91		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55