HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: PPIL1 (Q9Y3C6)
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1)
Gene: PPIL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.831

Property	Details
Experiments	25416956, 35271311
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Pro_isomerase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 166
+	Hs
		1160238 CPSF6_HUMAN (1-520): 4.07e-90: 289: 100.00		PPWD1_HUMAN (4-161): 2.32e-77: 243: 51.57
+	Hs
		216259 CPSF6_HUMAN (1-520): 4.07e-90: 289: 100.00		PPIH_HUMAN (3-159): 5.7e-76: 226: 39.18