HitPredict

Interactor 1: Q6PF37 (Q6PF37)
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)
Gene: smad9.S

Interactor 2: Q7ZTB4 (Q7ZTB4)
LEM domain containing 3 S homeolog (Nuclear membrane protein XMAN1)
Gene: lemd3.S

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	12642484
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 465 Xl			1 781
+	Xl
		1161303 Q6PF32_XENLA (7-465): 0: 632: 79.27		Q7ZTB4_XENLA (1-781): 0: 1098: 100.00
+	Xl
		1153626 Q6IRR4_XENLA (7-465): 0: 559: 54.58		Q7ZTB4_XENLA (1-781): 0: 1098: 100.00
+	Hs
		171465 SMAD9_HUMAN (1-465): 0: 653: 86.51		MAN1_HUMAN (5-778): 0: 983: 49.95
+	Hs
		1078782 SMAD1_HUMAN (7-465): 0: 627: 80.22		MAN1_HUMAN (5-778): 0: 983: 49.95
+	Hs
		1305895 SMAD5_HUMAN (4-465): 0: 625: 79.23		MAN1_HUMAN (5-778): 0: 983: 49.95
+	Hs
		950336 SMAD3_HUMAN (7-465): 0: 584: 59.09		MAN1_HUMAN (5-778): 0: 983: 49.95
+	Hs
		1078702 SMAD2_HUMAN (7-465): 0: 561: 54.58		MAN1_HUMAN (5-778): 0: 983: 49.95
+	Xl
		1193336 Q9YGP9_XENLA (12-459): 4.58e-144: 426: 32.85		Q7ZTB4_XENLA (1-781): 0: 1098: 100.00
+	Dm
		785457 MAD_DROME (3-465): 0: 617: 73.00		MAN1_DROME (184-761): 0: 611: 20.73
+	Dm
		332137 O96660_DROME (10-465): 0: 524: 50.51		MAN1_DROME (184-761): 0: 611: 20.73
+	Dm
		1137189 Q5U110_DROME (221-440): 5.23e-59: 205: 28.57		MAN1_DROME (184-761): 0: 611: 20.73
+	Hs
		641909 SMAD5_HUMAN (4-465): 0: 625: 79.23		U2AF2_HUMAN (605-744): 1.3e-31: 131: 20.13
+	Hs
		641717 SMAD3_HUMAN (7-465): 0: 584: 59.09		U2AF2_HUMAN (605-744): 1.3e-31: 131: 20.13
+	Hs
		641803 SMAD2_HUMAN (7-465): 0: 561: 54.58		U2AF2_HUMAN (605-744): 1.3e-31: 131: 20.13