Protein: HIF1A
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)

Gene: HIF1A
Organism: Homo sapiens
Interactions: 437
UniProt ID: Q16665

Gene Ontology (top 5):
GO:0000302 - response to reactive oxygen species
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822689

VHL
von Hippel-Lindau disease tumor suppressor

127

8

Small-scale

0.999

High

1067398

EP300
Histone acetyltransferase p300

62

20

Small-scale

0.997

High

693329

ARNT
Aryl hydrocarbon receptor nuclear translocator

63

20

Small-scale

0.997

High

1161387

EGLN1
Egl nine homolog 1

29

14

Small-scale

0.991

High

461533

HS90A
Heat shock protein HSP 90-alpha

21

17

Small-scale

0.989

High

1161418

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

17

2

Small-scale

0.988

High

1161341

CBP
CREB-binding protein

15

20

Small-scale

0.983

High

1161399

EGLN3
Prolyl hydroxylase EGLN3

16

14

Small-scale

0.982

High

1161363

EGLN2
Prolyl hydroxylase EGLN2

7

14

Small-scale

0.953

High

468426

HS90B
Heat shock protein HSP 90-beta

4

18

Small-scale

0.900

High

1161409

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

3

19

High-throughput

0.875

High

1161293

HIF1A
Hypoxia-inducible factor 1-alpha

4

19

Small-scale

0.860

High

1161449

HIF3A
Hypoxia-inducible factor 3-alpha

2

19

Small-scale

0.789

High

372153

MYC
Myc proto-oncogene protein

2

9

Small-scale

0.768

High

1028222

MDM2
E3 ubiquitin-protein ligase Mdm2

8

2

Small-scale

0.754

High

508049

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

11

5

Small-scale

0.751

High

761697

HSP74
Heat shock 70 kDa protein 4

8

8

Small-scale

0.750

High

992775

RACK1
Small ribosomal subunit protein RACK1

8

11

Small-scale

0.747

High

413930

P53
Cellular tumor antigen p53

9

7

Small-scale

0.746

High

764793

CTNB1
Catenin beta-1

7

20

Small-scale

0.746

High

1147039

ELOC
Elongin-C

9

2

Small-scale

0.745

High

1112855

CUL2
Cullin-2

7

9

Small-scale

0.742

High

1147170

ELOB
Elongin-B

7

2

Small-scale

0.736

High

1109770

HDAC1
Histone deacetylase 1

5

9

Small-scale

0.720

High

1161386

BHE41
Class E basic helix-loop-helix protein 41

1

19

Small-scale

0.715

High

940983

HDAC4
Histone deacetylase 4

5

11

Small-scale

0.713

High

1161426

SEPT9
Septin-9

5

1

Small-scale

0.709

High

1014528

SMAD3
Mothers against decapentaplegic homolog 3

4

8

Small-scale

0.707

High

833631

NAA10
N-alpha-acetyltransferase 10

5

0

Small-scale

0.699

High

1161342

KAT2B
Histone acetyltransferase KAT2B

4

10

Small-scale

0.696

High

585455

VEGFA
Vascular endothelial growth factor A, long form

6

0

Small-scale

0.695

High

238775

SSX4
Protein SSX4

5

0

High-throughput

0.683

High

827804

STAT3
Signal transducer and activator of transcription 3

4

6

Small-scale

0.683

High

464974

SP1
Transcription factor Sp1

3

10

Small-scale

0.681

High

991336

SUMO1
Small ubiquitin-related modifier 1

3

3

Small-scale

0.678

High

1099950

TIF1B
Transcription intermediary factor 1-beta

4

12

Small-scale

0.676

High

520093

ANDR
Androgen receptor

3

20

Small-scale

0.674

High

1161348

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

5

Small-scale

0.670

High

959592

MAX
Protein max

1

8

Small-scale

0.665

High

1161439

CHIP
E3 ubiquitin-protein ligase CHIP

3

14

Small-scale

0.664

High

1102554

MTA1
Metastasis-associated protein MTA1

2

3

Small-scale

0.657

High

396210

ESR1
Estrogen receptor

3

20

Small-scale

0.656

High

703608

MK01
Mitogen-activated protein kinase 1

3

3

Small-scale

0.655

High

1161308

VHLL
von Hippel-Lindau-like protein

1

8

Small-scale

0.648

High

1153763

NCOA1
Nuclear receptor coactivator 1

1

20

Small-scale

0.647

High

1122981

FHL2
Four and a half LIM domains protein 2

2

5

Small-scale

0.646

High

562074

LAMP2
Lysosome-associated membrane glycoprotein 2

3

2

Small-scale

0.640

High

881196

FAS
Fatty acid synthase

3

1

Small-scale

0.640

High

1008172

PRKDC
DNA-dependent protein kinase catalytic subunit

3

6

Small-scale

0.640

High

188293

HDAC3
Histone deacetylase 3

2

7

Small-scale

0.639

High

241818

PRKN
E3 ubiquitin-protein ligase parkin

2

6

Small-scale

0.634

High

833958

HNF4A
Hepatocyte nuclear factor 4-alpha

2

20

Small-scale

0.631

High

437585

MYL1
Myosin light chain 1/3, skeletal muscle isoform

2

3

High-throughput

0.628

High

535939

MYH3
Myosin-3

2

8

High-throughput

0.628

High

556854

MYH1
Myosin-1

2

8

High-throughput

0.628

High

563014

MYH6
Myosin-6

2

8

High-throughput

0.628

High

996464

ACTS
Actin, alpha skeletal muscle

2

1

High-throughput

0.628

High

1161433

MYH2
Myosin-2

2

8

High-throughput

0.628

High

1161458

MYH4
Myosin-4

2

8

High-throughput

0.628

High

756219

MCM7
DNA replication licensing factor MCM7

2

3

Small-scale

0.624

High

1161343

CSN5
COP9 signalosome complex subunit 5

2

2

Small-scale

0.624

High

1161357

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

10

Small-scale

0.624

High

1161445

RUVB2
RuvB-like 2

2

3

Small-scale

0.624

High

1161454

TRAF6
TNF receptor-associated factor 6

2

16

Small-scale

0.624

High

378596

EPO
Erythropoietin

3

0

Small-scale

0.623

High

1161334

HDAC7
Histone deacetylase 7

2

11

Small-scale

0.620

High

1161374

EPAS1
Endothelial PAS domain-containing protein 1

1

20

Small-scale

0.618

High

1161396

PLK3
Serine/threonine-protein kinase PLK3

2

1

Small-scale

0.611

High

320688

UBXN7
UBX domain-containing protein 7

2

3

Small-scale

0.611

High

681655

PSA4
Proteasome subunit alpha type-4

2

1

Small-scale

0.611

High

165338

PSA7
Proteasome subunit alpha type-7

2

0

Small-scale

0.607

High

253640

IMA7
Importin subunit alpha-7

2

13

Small-scale

0.602

High

993598

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.602

High

862184

YAP1
Transcriptional coactivator YAP1

2

6

Small-scale

0.601

High

584868

NQO1
NAD(P)H dehydrogenase [quinone] 1

2

0

Small-scale

0.598

High

832608

CASR
Extracellular calcium-sensing receptor

2

0

Small-scale

0.598

High

129735

CBX4
E3 SUMO-protein ligase CBX4

1

1

Small-scale

0.597

High

543578

ERR1
Steroid hormone receptor ERR1

1

20

Small-scale

0.597

High

842774

CDN2A
Cyclin-dependent kinase inhibitor 2A

2

6

Small-scale

0.595

High

911257

IMA5
Importin subunit alpha-5

2

13

Small-scale

0.595

High

132728

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

19

High-throughput

0.590

High

1161460

X5DP31
Aryl hydrocarbon receptor nuclear translocator 2

1

19

High-throughput

0.590

High

573120

KPYM
Pyruvate kinase PKM

1

3

Small-scale

0.589

High

1161325

FXL16
F-box/LRR-repeat protein 16

1

2

Small-scale

0.589

High

429976

JUN
Transcription factor Jun

2

12

Small-scale

0.584

High

443382

CDK1
Cyclin-dependent kinase 1

2

1

Small-scale

0.584

High

487368

PARP1
Poly [ADP-ribose] polymerase 1

2

6

Small-scale

0.584

High

488487

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

2

3

Small-scale

0.584

High

522104

BCL2
Apoptosis regulator Bcl-2

2

5

Small-scale

0.584

High

537236

HSP7C
Heat shock cognate 71 kDa protein

2

8

Small-scale

0.584

High

557328

SRC
Proto-oncogene tyrosine-protein kinase Src

2

7

Small-scale

0.584

High

558172

XRCC6
X-ray repair cross-complementing protein 6

2

5

Small-scale

0.584

High

559370

XRCC5
X-ray repair cross-complementing protein 5

2

5

Small-scale

0.584

High

979738

H4
Histone H4

2

6

High-throughput

0.584

High

1083371

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

7

Small-scale

0.584

High

1161329

TET1
Methylcytosine dioxygenase TET1

2

1

Small-scale

0.584

High

1161351

FBXW7
F-box/WD repeat-containing protein 7

2

8

Small-scale

0.584

High

1161393

TXNIP
Thioredoxin-interacting protein

2

2

Small-scale

0.584

High

1161408

UBP29
Ubiquitin carboxyl-terminal hydrolase 29

2

11

Small-scale

0.584

High

1161453

KDM3A
Lysine-specific demethylase 3A

2

1

Small-scale

0.584

High

482489

F16P1
Fructose-1,6-bisphosphatase 1

1

1

Small-scale

0.578

High

662584

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

3

Small-scale

0.578

High

1161450

RWDD3
RWD domain-containing protein 3

2

0

Small-scale

0.576

High

1161355

EAF2
ELL-associated factor 2

1

0

Small-scale

0.564

High

270249

MTG16
Protein CBFA2T3

1

1

Small-scale

0.561

High

343262

ERR2
Steroid hormone receptor ERR2

1

20

Small-scale

0.561

High

425528

ISG15
Ubiquitin-like protein ISG15

1

6

Small-scale

0.561

High

442734

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.561

High

828217

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

8

Small-scale

0.561

High

886910

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

Small-scale

0.561

High

976899

ERR3
Estrogen-related receptor gamma

1

20

Small-scale

0.561

High

1029851

RUNX1
Runt-related transcription factor 1

1

3

Small-scale

0.561

High

1116417

FHL1
Four and a half LIM domains protein 1

1

5

Small-scale

0.561

High

1116482

FHL3
Four and a half LIM domains protein 3

1

5

Small-scale

0.561

High

1119473

RUNX2
Runt-related transcription factor 2

1

3

Small-scale

0.561

High

1132725

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

Small-scale

0.561

High

1154836

NEDD8
Ubiquitin-like protein NEDD8

1

2

Small-scale

0.561

High

1161319

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

10

Small-scale

0.561

High

1161337

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

Small-scale

0.561

High

1161346

KAT5
Histone acetyltransferase KAT5

1

3

High-throughput

0.561

High

1161353

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

3

Small-scale

0.561

High

1161359

SAT2
Thialysine N-epsilon-acetyltransferase

1

1

Small-scale

0.561

High

1161362

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

Small-scale

0.561

High

1161390

RGAP1
Rac GTPase-activating protein 1

1

4

Small-scale

0.561

High

1161444

HDAC5
Histone deacetylase 5

1

11

Small-scale

0.561

High

1161446

RUVB1
RuvB-like 1

1

3

High-throughput

0.561

High

1161448

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

12

Small-scale

0.561

High

1161459

NEMO
NF-kappa-B essential modulator

1

17

Small-scale

0.561

High

956878

CXCR4
C-X-C chemokine receptor type 4

2

0

Small-scale

0.559

High

1161326

COMD1
COMM domain-containing protein 1

2

0

Small-scale

0.559

High

322948

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

10

Small-scale

0.552

High

1161371

NECD
Necdin

1

16

Small-scale

0.552

High

262083

NBN
Nibrin

1

0

Small-scale

0.537

High

963297

PFD3
Prefoldin subunit 3

1

0

Small-scale

0.537

High

1161394

KDM4C
Lysine-specific demethylase 4C

1

0

Small-scale

0.537

High

239582

MED14
Mediator of RNA polymerase II transcription subunit 14

1

14

Small-scale

0.536

High

297629

PIAS1
E3 SUMO-protein ligase PIAS1

1

5

High-throughput

0.536

High

484150

PGFRB
Platelet-derived growth factor receptor beta

1

4

High-throughput

0.536

High

766092

PCGF2
Polycomb group RING finger protein 2

1

2

Small-scale

0.536

High

876594

NEST
Nestin

1

9

High-throughput

0.536

High

881534

CDK8
Cyclin-dependent kinase 8

1

5

Small-scale

0.536

High

934680

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.536

High

1161301

CE350
Centrosome-associated protein 350

1

4

High-throughput

0.536

High

1161304

Z518A
Zinc finger protein 518A

1

1

High-throughput

0.536

High

1161309

NBEL1
Neurobeachin-like protein 1

1

8

High-throughput

0.536

High

1161311

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

2

Small-scale

0.536

High

1161349

MED12
Mediator of RNA polymerase II transcription subunit 12

1

19

Small-scale

0.536

High

1161356

FAF2
FAS-associated factor 2

1

3

High-throughput

0.536

High

1161367

MED15
Mediator of RNA polymerase II transcription subunit 15

1

20

Small-scale

0.536

High

1161372

TTC1
Tetratricopeptide repeat protein 1

1

10

High-throughput

0.536

High

1161385

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

6

High-throughput

0.536

High

1161405

PKHA5
Pleckstrin homology domain-containing family A member 5

1

1

High-throughput

0.536

High

1161412

RNC
Ribonuclease 3

1

2

Small-scale

0.536

High

1161428

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

Small-scale

0.536

High

1161430

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

8

High-throughput

0.536

High

1161434

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

Small-scale

0.536

High

1161321

RPTOR
Regulatory-associated protein of mTOR

1

12

Small-scale

0.534

High

351487

FTCD
Formimidoyltransferase-cyclodeaminase

1

0

Small-scale

0.529

High

366413

FA12
Coagulation factor XII

1

3

Small-scale

0.528

High

193344

MAFG
Transcription factor MafG

1

3

Small-scale

0.527

High

846915

ETV4
ETS translocation variant 4

1

16

Small-scale

0.527

High

882501

ARRB1
Beta-arrestin-1

1

1

Small-scale

0.515

High

389403

FINC
Fibronectin

1

0

High-throughput

0.513

High

1161300

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.513

High

1161303

MIC13
MICOS complex subunit MIC13

1

0

High-throughput

0.513

High

1161328

BANP
Protein BANP

1

0

High-throughput

0.513

High

1161365

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

1

0

High-throughput

0.513

High

1161383

NEUL
Neurolysin, mitochondrial

1

0

High-throughput

0.513

High

168856

PLD2
Phospholipase D2

1

1

Small-scale

0.512

High

1103755

PLD1
Phospholipase D1

1

1

Small-scale

0.512

High

1161314

UBE3B
Ubiquitin-protein ligase E3B

1

5

Small-scale

0.512

High

1161410

FBX8
F-box only protein 8

1

2

Small-scale

0.512

High

608975

XBP1
X-box-binding protein 1

1

0

Small-scale

0.512

High

138699

IMA4
Importin subunit alpha-4

1

13

Small-scale

0.501

High

142562

IMA3
Importin subunit alpha-3

1

13

Small-scale

0.501

High

170169

AURKA
Aurora kinase A

1

5

High-throughput

0.501

High

179052

IMA6
Importin subunit alpha-6

1

13

Small-scale

0.501

High

253410

MAFK
Transcription factor MafK

1

3

Small-scale

0.501

High

549168

CDK4
Cyclin-dependent kinase 4

1

7

High-throughput

0.501

High

605697

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

Small-scale

0.501

High

639608

SAT1
Diamine acetyltransferase 1

1

1

Small-scale

0.501

High

648532

FGFR4
Fibroblast growth factor receptor 4

1

4

High-throughput

0.501

High

710270

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.501

High

718823

CCND2
G1/S-specific cyclin-D2

1

4

High-throughput

0.501

High

728270

AKT1
RAC-alpha serine/threonine-protein kinase

1

6

High-throughput

0.501

High

767228

MERL
Merlin

1

2

High-throughput

0.501

High

771002

RORA
Nuclear receptor ROR-alpha

1

20

Small-scale

0.501

High

842921

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

6

High-throughput

0.501

High

858668

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

14

High-throughput

0.501

High

877127

KC1D
Casein kinase I isoform delta

1

8

Small-scale

0.501

High

883253

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.501

High

902484

RT29
Small ribosomal subunit protein mS29

1

1

Small-scale

0.501

High

1025360

CDK6
Cyclin-dependent kinase 6

1

7

High-throughput

0.501

High

1060265

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

5

Small-scale

0.501

High

1061584

FOXM1
Forkhead box protein M1

1

11

Small-scale

0.501

High

1097097

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

13

High-throughput

0.501

High

1102177

ATM
Serine-protein kinase ATM

1

6

Small-scale

0.501

High

1118407

PTK6
Protein-tyrosine kinase 6

1

7

Small-scale

0.501

High

1150232

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.501

High

1154368

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.501

High

1161333

IASPP
RelA-associated inhibitor

1

7

Small-scale

0.501

High

1161340

HDAC2
Histone deacetylase 2

1

8

Small-scale

0.501

High

1161352

E2F7
Transcription factor E2F7

1

5

Small-scale

0.501

High

1161368

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

10

Small-scale

0.501

High

1161384

GLIS2
Zinc finger protein GLIS2

1

2

High-throughput

0.501

High

1161411

LATS2
Serine/threonine-protein kinase LATS2

1

9

High-throughput

0.501

High

1161437

FZR1
Fizzy-related protein homolog

1

11

High-throughput

0.501

High

857470

NOTC1
Neurogenic locus notch homolog protein 1

1

1

Small-scale

0.500

High

1161350

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.493

High

697129

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

Small-scale

0.480

High

906672

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

Small-scale

0.480

High

1092050

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

0

Small-scale

0.480

High

1161296

ZC12A
Endoribonuclease ZC3H12A

1

0

Small-scale

0.480

High

1161298

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

Small-scale

0.480

High

1161388

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

Small-scale

0.480

High

61508

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

123110

DX39A
ATP-dependent RNA helicase DDX39A

1

2

High-throughput

0.479

High

134043

IPO5
Importin-5

1

2

High-throughput

0.479

High

167910

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

7

Small-scale

0.479

High

172866

XPO1
Exportin-1

1

9

Small-scale

0.479

High

173705

BTAF1
TATA-binding protein-associated factor 172

1

10

High-throughput

0.479

High

186757

P73
Tumor protein p73

1

7

Small-scale

0.479

High

210497

SEPT4
Septin-4

1

1

Small-scale

0.479

High

219737

FOXO3
Forkhead box protein O3

1

19

Small-scale

0.479

High

220914

XPOT
Exportin-T

1

7

High-throughput

0.479

High

227891

MYO1B
Unconventional myosin-Ib

1

6

High-throughput

0.479

High

255640

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

1

High-throughput

0.479

High

258903

DNJA2
DnaJ homolog subfamily A member 2

1

11

High-throughput

0.479

High

274597

DNJB6
DnaJ homolog subfamily B member 6

1

11

High-throughput

0.479

High

289561

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.479

High

295506

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

2

Small-scale

0.479

High

321554

PRP6
Pre-mRNA-processing factor 6

1

1

High-throughput

0.479

High

322729

RHBT3
Rho-related BTB domain-containing protein 3

1

5

Small-scale

0.479

High

323397

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

Small-scale

0.479

High

327600

ELP1
Elongator complex protein 1

1

1

High-throughput

0.479

High

347057

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.479

High

348517

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

High-throughput

0.479

High

355223

ACL6A
Actin-like protein 6A

1

3

High-throughput

0.479

High

425988

CP1A2
Cytochrome P450 1A2

1

1

Small-scale

0.479

High

457100

CAN1
Calpain-1 catalytic subunit

1

1

Small-scale

0.479

High

540023

BCR
Breakpoint cluster region protein

1

3

Small-scale

0.479

High

570898

MIF
Macrophage migration inhibitory factor

1

2

Small-scale

0.479

High

577777

PLAK
Junction plakoglobin

1

18

Small-scale

0.479

High

590288

MUC1
Mucin-1

1

5

Small-scale

0.479

High

591668

H2AX
Histone H2AX

1

1

Small-scale

0.479

High

593121

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.479

High

601699

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

Small-scale

0.479

High

610344

PRS6A
26S proteasome regulatory subunit 6A

1

12

Small-scale

0.479

High

613059

EGR1
Early growth response protein 1

1

3

Small-scale

0.479

High

622455

ELK1
ETS domain-containing protein Elk-1

1

17

Small-scale

0.479

High

623362

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

Small-scale

0.479

High

651346

CBL
E3 ubiquitin-protein ligase CBL

1

13

Small-scale

0.479

High

652525

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

Small-scale

0.479

High

667885

CDK2
Cyclin-dependent kinase 2

1

1

Small-scale

0.479

High

669914

MCM3
DNA replication licensing factor MCM3

1

6

Small-scale

0.479

High

675524

TYY1
Transcriptional repressor protein YY1

1

1

Small-scale

0.479

High

679171

DNJB1
DnaJ homolog subfamily B member 1

1

9

Small-scale

0.479

High

688248

TTP
mRNA decay activator protein ZFP36

1

5

Small-scale

0.479

High

711362

SHC1
SHC-transforming protein 1

1

3

Small-scale

0.479

High

717831

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.479

High

722715

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

1

High-throughput

0.479

High

727824

DNJA1
DnaJ homolog subfamily A member 1

1

11

High-throughput

0.479

High

730618

1433S
14-3-3 protein sigma

1

3

Small-scale

0.479

High

732609

ARRB2
Beta-arrestin-2

1

1

Small-scale

0.479

High

761414

HS71L
Heat shock 70 kDa protein 1-like

1

8

Small-scale

0.479

High

769731

RFC4
Replication factor C subunit 4

1

4

High-throughput

0.479

High

769867

RFC2
Replication factor C subunit 2

1

4

High-throughput

0.479

High

783071

TCF7
Transcription factor 7

1

20

Small-scale

0.479

High

799160

BRCA1
Breast cancer type 1 susceptibility protein

1

10

Small-scale

0.479

High

827193

ARL1
ADP-ribosylation factor-like protein 1

1

1

High-throughput

0.479

High

829090

RFC5
Replication factor C subunit 5

1

4

High-throughput

0.479

High

829220

RFC3
Replication factor C subunit 3

1

4

High-throughput

0.479

High

839284

MTOR
Serine/threonine-protein kinase mTOR

1

7

High-throughput

0.479

High

841756

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

846321

MATR3
Matrin-3

1

2

High-throughput

0.479

High

846617

MSH2
DNA mismatch repair protein Msh2

1

1

High-throughput

0.479

High

857116

NSF
Vesicle-fusing ATPase

1

2

High-throughput

0.479

High

862858

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.479

High

868089

AL1A3
Retinaldehyde dehydrogenase 3

1

1

High-throughput

0.479

High

891589

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

897843

CDK9
Cyclin-dependent kinase 9

1

5

High-throughput

0.479

High

905417

HCFC1
Host cell factor 1

1

3

High-throughput

0.479

High

910535

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.479

High

912903

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

2

High-throughput

0.479

High

913330

MSH6
DNA mismatch repair protein Msh6

1

2

High-throughput

0.479

High

931668

RD23B
UV excision repair protein RAD23 homolog B

1

1

Small-scale

0.479

High

939191

SUMO3
Small ubiquitin-related modifier 3

1

3

Small-scale

0.479

High

958280

ARP2
Actin-related protein 2

1

2

High-throughput

0.479

High

983825

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

Small-scale

0.479

High

994564

YBOX1
Y-box-binding protein 1

1

1

High-throughput

0.479

High

1045344

TF65
Transcription factor p65

1

10

Small-scale

0.479

High

1046367

UBXN1
UBX domain-containing protein 1

1

2

High-throughput

0.479

High

1055221

MTG8
Protein CBFA2T1

1

1

Small-scale

0.479

High

1093236

FLII
Protein flightless-1 homolog

1

2

High-throughput

0.479

High

1105303

SF3B2
Splicing factor 3B subunit 2

1

1

High-throughput

0.479

High

1106198

MYO9B
Unconventional myosin-IXb

1

8

High-throughput

0.479

High

1106556

SMAD4
Mothers against decapentaplegic homolog 4

1

8

Small-scale

0.479

High

1107767

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

1109281

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.479

High

1117051

RUNX3
Runt-related transcription factor 3

1

3

Small-scale

0.479

High

1121406

KEAP1
Kelch-like ECH-associated protein 1

1

3

Small-scale

0.479

High

1137049

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

2

Small-scale

0.479

High

1138257

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1144006

TEBP
Prostaglandin E synthase 3

1

3

Small-scale

0.479

High

1146686

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.479

High

1146904

PCBP2
Poly(rC)-binding protein 2

1

1

High-throughput

0.479

High

1150971

PCH2
Pachytene checkpoint protein 2 homolog

1

9

High-throughput

0.479

High

1157735

DDB1
DNA damage-binding protein 1

1

7

High-throughput

0.479

High

1161294

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.479

High

1161299

DCAF8
DDB1- and CUL4-associated factor 8

1

10

Small-scale

0.479

High

1161302

ECM29
Proteasome adapter and scaffold protein ECM29

1

10

High-throughput

0.479

High

1161305

OTU7B
OTU domain-containing protein 7B

1

2

Small-scale

0.479

High

1161310

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

8

Small-scale

0.479

High

1161312

TBA1A
Tubulin alpha-1A chain

1

3

Small-scale

0.479

High

1161313

MON2
Protein MON2 homolog

1

1

High-throughput

0.479

High

1161316

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

3

High-throughput

0.479

High

1161317

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

8

Small-scale

0.479

High

1161324

PIAS4
E3 SUMO-protein ligase PIAS4

1

5

Small-scale

0.479

High

1161327

SIR6
NAD-dependent protein deacylase sirtuin-6

1

10

Small-scale

0.479

High

1161336

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

1161338

NR4A3
Nuclear receptor subfamily 4 group A member 3

1

20

Small-scale

0.479

High

1161339

GCN1
Stalled ribosome sensor GCN1

1

12

High-throughput

0.479

High

1161347

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

6

Small-scale

0.479

High

1161358

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

6

High-throughput

0.479

High

1161364

EP400
E1A-binding protein p400

1

10

High-throughput

0.479

High

1161366

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

2

Small-scale

0.479

High

1161369

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.479

High

1161370

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

1161373

CDC6
Cell division control protein 6 homolog

1

4

Small-scale

0.479

High

1161376

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.479

High

1161389

WWTR1
WW domain-containing transcription regulator protein 1

1

6

Small-scale

0.479

High

1161391

RBM38
RNA-binding protein 38

1

1

Small-scale

0.479

High

1161392

P63
Tumor protein 63

1

7

Small-scale

0.479

High

1161395

UN45A
Protein unc-45 homolog A

1

19

High-throughput

0.479

High

1161397

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

1161400

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.479

High

1161402

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

1

Small-scale

0.479

High

1161403

NANOG
Homeobox protein NANOG

1

12

Small-scale

0.479

High

1161406

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

2

Small-scale

0.479

High

1161407

XPO5
Exportin-5

1

7

High-throughput

0.479

High

1161413

DCA13
DDB1- and CUL4-associated factor 13

1

11

Small-scale

0.479

High

1161417

RNF12
E3 ubiquitin-protein ligase RLIM

1

2

Small-scale

0.479

High

1161421

KLHL8
Kelch-like protein 8

1

3

Small-scale

0.479

High

1161422

HDAC6
Protein deacetylase HDAC6

1

11

Small-scale

0.479

High

1161424

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

3

High-throughput

0.479

High

1161427

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

8

Small-scale

0.479

High

1161431

ING1
Inhibitor of growth protein 1

1

4

Small-scale

0.479

High

1161436

ASC
Apoptosis-associated speck-like protein containing a CARD

1

1

Small-scale

0.479

High

1161440

FAF1
FAS-associated factor 1

1

4

High-throughput

0.479

High

1161443

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

6

Small-scale

0.479

High

1161452

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.479

High

1161457

SRPRB
Signal recognition particle receptor subunit beta

1

1

High-throughput

0.479

High

134305

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.458

High

161539

ZN197
Zinc finger protein 197

1

0

Small-scale

0.458

High

221133

SPY2
Protein sprouty homolog 2

1

0

Small-scale

0.458

High

229442

IDH3B
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

1

0

High-throughput

0.458

High

288955

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.458

High

324902

HEXI1
Protein HEXIM1

1

0

Small-scale

0.458

High

359666

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.458

High

365390

PGK1
Phosphoglycerate kinase 1

1

0

Small-scale

0.458

High

424599

PAI1
Plasminogen activator inhibitor 1

1

0

Small-scale

0.458

High

539060

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.458

High

555818

ACE
Angiotensin-converting enzyme

1

0

Small-scale

0.458

High

608281

EGLN
Endoglin

1

0

Small-scale

0.458

High

608884

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.458

High

722974

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.458

High

776920

CHKA
Choline kinase alpha

1

0

Small-scale

0.458

High

832473

LEP
Leptin

1

0

Small-scale

0.458

High

902194

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.458

High

936596

ELL
RNA polymerase II elongation factor ELL

1

0

Small-scale

0.458

High

958776

ARF3
ADP-ribosylation factor 3

1

0

High-throughput

0.458

High

1004628

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1005877

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1009614

PHLD
Phosphatidylinositol-glycan-specific phospholipase D

1

0

Small-scale

0.458

High

1015223

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.458

High

1127563

FAT1
Protocadherin Fat 1

1

0

High-throughput

0.458

High

1131953

MVP
Major vault protein

1

0

Small-scale

0.458

High

1152513

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.458

High

1161306

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1161307

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1161320

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.458

High

1161322

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

1161323

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

1161330

FBX30
F-box only protein 30

1

0

Small-scale

0.458

High

1161332

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

Small-scale

0.458

High

1161344

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.458

High

1161345

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

0

High-throughput

0.458

High

1161360

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.458

High

1161361

DCNL1
DCN1-like protein 1

1

0

Small-scale

0.458

High

1161378

PELO
Protein pelota homolog

1

0

High-throughput

0.458

High

1161380

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.458

High

1161381

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.458

High

1161382

ANGL4
Angiopoietin-related protein 4

1

0

Small-scale

0.458

High

1161398

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.458

High

1161404

ELP3
Elongator complex protein 3

1

0

High-throughput

0.458

High

1161415

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.458

High

1161419

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.458

High

1161420

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

1161432

RALY
RNA-binding protein Raly

1

0

High-throughput

0.458

High

1161438

NDRG2
Protein NDRG2

1

0

Small-scale

0.458

High

1161441

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

1161442

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

1161447

CNPY2
Protein canopy homolog 2

1

0

Small-scale

0.458

High

1161451

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.458

High

1161455

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.458

High

1161456

HLPDA
Hypoxia-inducible lipid droplet-associated protein

1

0

Small-scale

0.458

High

997749

CSK21
Casein kinase II subunit alpha

1

6

Small-scale

0.445

High

445632

CEAM5
Cell adhesion molecule CEACAM5

1

1

Small-scale

0.437

High

460827

CATB
Cathepsin B

1

1

High-throughput

0.437

High

1037061

MUC3A
Mucin-3A

1

4

Small-scale

0.437

High

1147520

UBE3C
Ubiquitin-protein ligase E3C

1

8

High-throughput

0.437

High

1161297

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

1

High-throughput

0.437

High

1161375

RNF5
E3 ubiquitin-protein ligase RNF5

1

8

Small-scale

0.437

High

1161416

ATD3A
ATPase family AAA domain-containing protein 3A

1

3

High-throughput

0.437

High

1161425

ABCF2
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.437

High

1161429

DNAI1
Dynein axonemal intermediate chain 1

1

4

Small-scale

0.437

High

1161435

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

Small-scale

0.437

High

1161335

DGCR8
Microprocessor complex subunit DGCR8

1

0

Small-scale

0.426

High

1161423

SUCO
SUN domain-containing ossification factor

1

0

Small-scale

0.391

High

1105462

OS9
Protein OS-9

2

0

Small-scale

0.336

High

518570

ADX
Adrenodoxin, mitochondrial

1

0

High-throughput

0.279

Low

1161318

LYSM2
LysM and putative peptidoglycan-binding domain-containing protein 2

1

0

High-throughput

0.279

Low

1161377

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

66205

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.249

Low

184848

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.249

Low

882688

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.249

Low

944262

TMM33
Transmembrane protein 33

1

0

High-throughput

0.249

Low

1036372

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

1158746

KCMB1
Calcium-activated potassium channel subunit beta-1

1

0

Small-scale

0.249

Low

1161295

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.249

Low

1161315

VTCN1
V-set domain-containing T-cell activation inhibitor 1

1

0

Small-scale

0.249

Low

1161331

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.249

Low

1161354

RHDF1
Inactive rhomboid protein 1

1

0

Small-scale

0.249

Low

1161379

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.249

Low

1161401

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.249

Low

1161414

FBX28
F-box only protein 28

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025