Protein: EYA2
Eyes absent homolog 2 (EC 3.1.3.48)

Gene: EYA2
Organism: Homo sapiens
Interactions: 120
UniProt ID: O00167

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

118562

SIX1
Homeobox protein SIX1

7

20

Small-scale

0.962

High

118611

SIX2
Homeobox protein SIX2

2

20

High-throughput

0.811

High

118619

SIX4
Homeobox protein SIX4

2

20

Small-scale

0.757

High

118525

BAG3
BAG family molecular chaperone regulator 3

3

2

High-throughput

0.653

High

118608

ACAD9
Complex I assembly factor ACAD9, mitochondrial

3

0

High-throughput

0.628

High

118510

EYA2
Eyes absent homolog 2

1

13

High-throughput

0.618

High

118524

EYA4
Eyes absent homolog 4

1

14

High-throughput

0.618

High

118513

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

4

High-throughput

0.606

High

118521

TPC6A
Trafficking protein particle complex subunit 6A

2

1

High-throughput

0.606

High

118531

RU1C
U1 small nuclear ribonucleoprotein C

2

4

High-throughput

0.606

High

118543

RFX2
DNA-binding protein RFX2

2

3

High-throughput

0.606

High

118545

PAX9
Paired box protein Pax-9

2

9

High-throughput

0.606

High

118546

LEG4
Galectin-4

2

3

High-throughput

0.606

High

118554

CDK18
Cyclin-dependent kinase 18

2

2

High-throughput

0.606

High

118555

TLE5
TLE family member 5

2

5

High-throughput

0.606

High

118556

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.606

High

118571

MED25
Mediator of RNA polymerase II transcription subunit 25

2

1

High-throughput

0.606

High

118573

POGZ
Pogo transposable element with ZNF domain

2

2

High-throughput

0.606

High

118574

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

9

High-throughput

0.606

High

118580

CTSR1
Cation channel sperm-associated protein 1

2

1

High-throughput

0.606

High

118587

TEKT4
Tektin-4

2

1

High-throughput

0.606

High

118589

TFG
Protein TFG

2

10

High-throughput

0.606

High

118596

TEKT5
Tektin-5

2

1

High-throughput

0.606

High

118604

TRAF4
TNF receptor-associated factor 4

2

8

High-throughput

0.606

High

118607

DUS21
Dual specificity protein phosphatase 21

2

1

High-throughput

0.606

High

118609

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

2

High-throughput

0.606

High

118544

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.580

High

118572

ATOSB
Atos homolog protein B

2

0

High-throughput

0.580

High

118598

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.580

High

118614

SPG21
Maspardin

2

0

High-throughput

0.580

High

118527

AP2A
Transcription factor AP-2-alpha

2

2

High-throughput

0.576

High

118623

FBX7
F-box only protein 7

1

1

Small-scale

0.561

High

60530

VP37C
Vacuolar protein sorting-associated protein 37C

2

10

High-throughput

0.553

High

118591

RBPMS
RNA-binding protein with multiple splicing

1

2

High-throughput

0.541

High

118538

CALR
Calreticulin

1

3

High-throughput

0.536

High

118561

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

118526

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

5

Small-scale

0.527

High

118528

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.513

High

118552

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

4

High-throughput

0.494

High

118570

LMTK1
Serine/threonine-protein kinase LMTK1

1

7

High-throughput

0.494

High

118536

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

5

Small-scale

0.481

High

118597

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

2

High-throughput

0.481

High

118511

ARI1A
AT-rich interactive domain-containing protein 1A

1

13

High-throughput

0.479

High

118512

KMT2D
Histone-lysine N-methyltransferase 2D

1

17

High-throughput

0.479

High

118514

ZN609
Zinc finger protein 609

1

9

High-throughput

0.479

High

118515

SC16A
Protein transport protein Sec16A

1

12

High-throughput

0.479

High

118516

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

118518

SCO2
Protein SCO2 homolog, mitochondrial

1

3

High-throughput

0.479

High

118520

NCOR1
Nuclear receptor corepressor 1

1

16

High-throughput

0.479

High

118522

SCO1
Protein SCO1 homolog, mitochondrial

1

3

High-throughput

0.479

High

118529

4F2
Amino acid transporter heavy chain SLC3A2

1

1

High-throughput

0.479

High

118532

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

118533

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.479

High

118534

NDKA
Nucleoside diphosphate kinase A

1

1

High-throughput

0.479

High

118535

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

1

High-throughput

0.479

High

118539

DUS1
Dual specificity protein phosphatase 1

1

1

High-throughput

0.479

High

118541

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

2

High-throughput

0.479

High

118542

KPB1
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform

1

2

High-throughput

0.479

High

118547

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.479

High

118549

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.479

High

118553

TLE3
Transducin-like enhancer protein 3

1

14

High-throughput

0.479

High

118557

PUM1
Pumilio homolog 1

1

1

High-throughput

0.479

High

118559

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

118565

PRC2B
Protein PRRC2B

1

20

High-throughput

0.479

High

118566

RBM20
RNA-binding protein 20

1

4

High-throughput

0.479

High

118568

CEP85
Centrosomal protein of 85 kDa

1

6

High-throughput

0.479

High

118569

BCOR
BCL-6 corepressor

1

7

High-throughput

0.479

High

118576

RAVR1
Ribonucleoprotein PTB-binding 1

1

10

High-throughput

0.479

High

118579

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

17

High-throughput

0.479

High

118581

ARI1B
AT-rich interactive domain-containing protein 1B

1

14

High-throughput

0.479

High

118582

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

2

High-throughput

0.479

High

118583

DCA11
DDB1- and CUL4-associated factor 11

1

8

High-throughput

0.479

High

118592

KPBB
Phosphorylase b kinase regulatory subunit beta

1

2

High-throughput

0.479

High

118599

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

118600

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

118602

LZTS2
Leucine zipper putative tumor suppressor 2

1

8

High-throughput

0.479

High

118615

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

1

High-throughput

0.479

High

118618

TRPS1
Zinc finger transcription factor Trps1

1

11

High-throughput

0.479

High

118622

SNX6
Sorting nexin-6

1

2

High-throughput

0.479

High

118625

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

61252

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

118517

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.458

High

118519

NBN
Nibrin

1

0

High-throughput

0.458

High

118530

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

118540

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

118548

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.458

High

118560

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.458

High

118563

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.458

High

118577

PNKD
Probable hydrolase PNKD

1

0

High-throughput

0.458

High

118601

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

118603

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

High-throughput

0.458

High

118620

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

118590

AP2C
Transcription factor AP-2 gamma

1

2

High-throughput

0.457

High

118537

ANFC
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]

1

1

High-throughput

0.437

High

118558

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

118564

TGO1
Transport and Golgi organization protein 1 homolog

1

5

High-throughput

0.437

High

118567

CCD18
Coiled-coil domain-containing protein 18

1

5

High-throughput

0.437

High

118575

CC28A
Coiled-coil domain-containing protein 28A

1

1

High-throughput

0.437

High

118584

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.437

High

118595

GMPPA
Mannose-1-phosphate guanyltransferase alpha

1

1

High-throughput

0.437

High

118605

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

1

High-throughput

0.437

High

118613

DJB12
DnaJ homolog subfamily B member 12

1

3

High-throughput

0.437

High

118624

GMPPB
Mannose-1-phosphate guanyltransferase beta

1

1

High-throughput

0.437

High

118585

DDI1
Protein DDI1 homolog 1

1

8

High-throughput

0.417

High

118578

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.316

High

118606

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

63701

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.269

Low

118523

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.249

Low

118550

DCD
Dermcidin

1

0

High-throughput

0.249

Low

118551

FAM3A
Protein FAM3A

1

0

High-throughput

0.249

Low

118586

THEM6
Protein THEM6

1

0

High-throughput

0.249

Low

118588

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.249

Low

118593

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.249

Low

118594

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

118610

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

118612

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

0

High-throughput

0.249

Low

118616

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.249

Low

118617

CING
Cingulin

1

0

High-throughput

0.249

Low

118621

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024