HitPredict

Interactor 1: SPSB3 (Q6PJ21)
SPRY domain-containing SOCS box protein 3 (SSB-3)
Gene: SPSB3

Interactor 2: RPGR (Q92834)
X-linked retinitis pigmentosa GTPase regulator
Gene: RPGR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1020
+	Hs
		578455 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		RCC1_HUMAN (2-371): 2.37e-89: 294: 22.22
+	Hs
		1172064 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		RCC2_HUMAN (136-472): 8.43e-63: 224: 17.20
+	Hs
		319948 DDX1_HUMAN (104-304): 1.68e-47: 173: 18.14		HERC2_HUMAN (5-157): 9.46e-45: 179: 26.99
+	Hs
		1125817 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		HERC4_HUMAN (4-190): 1.22e-51: 199: 23.62
+	Hs
		319851 HERC1_HUMAN (78-281): 3.33e-41: 156: 17.27		HERC2_HUMAN (5-157): 9.46e-45: 179: 26.99
+	Hs
		319890 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		HERC2_HUMAN (5-157): 9.46e-45: 179: 26.99
+	Hs
		1077997 HERC1_HUMAN (78-281): 3.33e-41: 156: 17.27		HERC1_HUMAN (204-413): 3.57e-35: 148: 20.93
+	Hs
		1078017 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		HERC1_HUMAN (204-413): 3.57e-35: 148: 20.93
+	Hs
		1171246 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		RCC1L_HUMAN (160-383): 2e-33: 137: 22.73
+	Hs
		962443 HNRPU_HUMAN (59-307): 4.13e-55: 195: 17.36		HERC5_HUMAN (36-188): 3.1e-13: 76.3: 27.74
+	Hs
		1140837 RN123_HUMAN (55-299): 5.18e-49: 178: 13.31		HERC5_HUMAN (36-188): 3.1e-13: 76.3: 27.74
+	Mm
		1118130 TRI67_MOUSE (105-276): 9.38e-40: 151: 21.47		HERC2_MOUSE (255-477): 2.79e-20: 99.7: 18.22